Background Wearable sensor technologies have the potential to improve monitoring in
people with multiple sclerosis (MS) and inform timely disease management decisions …

Fatigue is one of the most common multiple sclerosis (MS) symptoms. Despite this,
monitoring and measuring fatigue (subjective lack of energy)–and fatigability (objectively …

In recent years, there has been a growing interest in developing and evaluating gait analysis
algorithms based on inertial measurement unit (IMU) data, which has important implications …

Measures of human motion provide a rich source of health and physiological status
information. This paper provides examples of motion-based biomarkers in the form of …

Numerous disorders are characterised by fatigue as a highly disabling symptom. Fatigue
plays a particularly important clinical role in multiple sclerosis (MS) where it exerts a …

In the last decade, fatigue in clinical populations has been re-conceptualized, including
dimensions such as perceived fatigue (trait and state fatigue) and fatigability. The aim of this …

Two-thirds of people with Multiple Sclerosis (PwMS) have walking disabilities. Considering
the literature, prolonged tests, such as the 6 min walk test, better reflect their everyday life …

Background Trait and state physical fatigue (trait-PF and state-PF) negatively impact many
people with multiple sclerosis (pwMS) but are challenging symptoms to measure. In this …

Background Wrist-worn inertial sensors are used in digital health for evaluating mobility in
real-world environments. Preceding the estimation of spatiotemporal gait parameters within …

Fatigue of the lower-extremity muscles can induce gait instability and increases the risk of
injury among older adults. Recognizing muscle fatigue can facilitate a timely response and …