Pulmonary fibrosis and COVID-19: the potential role for antifibrotic therapy

PM George, AU Wells, RG Jenkins - The Lancet Respiratory …, 2020 - thelancet.com
In December, 2019, reports emerged from Wuhan, China, of a severe acute respiratory
disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). By the …

Idiopathic pulmonary fibrosis: state of the art for 2023

AJ Podolanczuk, CC Thomson… - European …, 2023 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease characterised by
worsening respiratory symptoms and physiological impairment. Increasing awareness of the …

Lung fibrosis after COVID-19: treatment prospects

E Bazdyrev, P Rusina, M Panova, F Novikov… - Pharmaceuticals, 2021 - mdpi.com
At the end of 2019, a highly contagious infection began its ominous conquest of the world. It
was soon discovered that the disease was caused by a novel coronavirus designated as …

Emerging cellular and molecular determinants of idiopathic pulmonary fibrosis

THG Phan, P Paliogiannis, GK Nasrallah… - Cellular and Molecular …, 2021 - Springer
Idiopathic pulmonary fibrosis (IPF), the most common form of idiopathic interstitial
pneumonia, is a progressive, irreversible, and typically lethal disease characterized by an …

The lung microbiome: progress and promise

SA Whiteside, JE McGinniss… - The Journal of Clinical …, 2021 - Am Soc Clin Investig
The healthy lung was long thought of as sterile, but recent advances using molecular
sequencing approaches have detected bacteria at low levels. Healthy lung bacteria largely …

Acute exacerbation of idiopathic pulmonary fibrosis. An international working group report

HR Collard, CJ Ryerson, TJ Corte… - American journal of …, 2016 - atsjournals.org
Acute exacerbation of idiopathic pulmonary fibrosis has been defined as an acute, clinically
significant, respiratory deterioration of unidentifiable cause. The objective of this …

[HTML][HTML] Viral infection increases the risk of idiopathic pulmonary fibrosis: a meta-analysis

G Sheng, P Chen, Y Wei, H Yue, J Chu, J Zhao… - Chest, 2020 - Elsevier
Background Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrotic lung
disease with a poor prognosis. Although many factors have been identified that possibly …

[HTML][HTML] SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis

D Wendisch, O Dietrich, T Mari, S von Stillfried… - Cell, 2021 - cell.com
Summary COVID-19-induced" acute respiratory distress syndrome"(ARDS) is associated
with prolonged respiratory failure and high mortality, but the mechanistic basis of lung injury …

Pathogenesis of idiopathic pulmonary fibrosis

PJ Wolters, HR Collard, KD Jones - Annual Review of Pathology …, 2014 - annualreviews.org
Idiopathic pulmonary fibrosis (IPF) is a fibrosing interstitial lung disease associated with
aging that is characterized by the histopathological pattern of usual interstitial pneumonia …

The role of bacteria in the pathogenesis and progression of idiopathic pulmonary fibrosis

PL Molyneaux, MJ Cox, SAG Willis-Owen… - American journal of …, 2014 - atsjournals.org
Rationale: Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease of unknown
cause that leads to respiratory failure and death within 5 years of diagnosis. Overt …