Chronic kidney disease (CKD) affects over 850 million people globally, and there is an
urgent need to prevent its development and progression. During the last decade, new …

The spectrum of cardiorenal and metabolic diseases comprises many disorders, including
obesity, type 2 diabetes (T2D), chronic kidney disease (CKD), atherosclerotic cardiovascular …

Arterial stiffness and hypertension are closely related in pathophysiology. Chronic high
blood pressure (BP) can lead to arterial wall damage by mechanical stress, endothelial …

Uric acid (UA) is the end product of purine metabolism, and its concentration in blood can
increase in humans, great apes, and dalmatian dogs as a consequence of a genetic …

This review critiques the literature supporting clinical assessment and management of
cardiovascular disease and cardiovascular disease risk stratification with brachial-ankle …

BACKGROUND: Arterial stiffness, as measured by arterial pulse wave velocity (PWV), is an
established biomarker for cardiovascular risk and target-organ damage in individuals with …

Resistant hypertension (RH) is a severe form of hypertension associated with increased
cardiovascular risk. Although true RH affects less than 10% of the patients receiving …

In their recent guidelines, the European Society of Hypertension upgraded β blockers,
putting them on equal footing with thiazide diuretics, renin–angiotensin system blockers (eg …

Clinical practice guidelines are ideally suited to the provision of advice on the prevention,
diagnosis, evaluation, and management of high blood pressure (BP). The recently published …

More than 90% of patients developing heart failure (HF) have hypertension. The most
frequent concomitant conditions are type-2 diabetes mellitus, obesity, atrial fibrillation, and …