Expanding epidemiologic and physiologic data suggest that urinary stone disease is best
conceptualized as a chronic metabolic condition punctuated by symptomatic, preventable …

Urolithiasis affects around 10% of the US population with an increasing rate of prevalence,
recurrence and penetrance. The causes for the formation of most urinary calculi remain …

With the dramatic increase in nanotechnologies, it has become increasingly likely that food
crops will be exposed to excess engineered nanoparticles (NPs). In this study, cucumber …

The lifetime prevalence of kidney stones is around 10% and incidence rates are increasing.
Diet may be an important determinant of kidney stone development. Our objective was to …

Nephrolithiasis is highly prevalent and associated with the increased risk of kidney cancer.
The tumor suppressor von Hippel-Lindau (VHL) is critical for renal cancer development …

Ectopic calcification is a driving force for a variety of diseases, including kidney stones and
atherosclerosis, but initiating factors remain largely unknown. Given its importance in …

Background Trace metals are essential trace elements for the human body, but insufficient
or excessive levels of metal ions can lead to the development of disease. The purpose of …

Background The prevalence of kidney stones is on the rise globally. Several risk factors,
including lifestyle, contribute to the formation of kidney stones. Nevertheless, there is a …

Background Current studies have reported conflicting associations between circulating
micronutrient levels and kidney stone disease (KSD). We aimed to elucidate the causal …

Individuals with urinary stone disease (USD) exhibit dysbiosis in the urinary tract and the
loss of Lactobacillus that promote urinary tract health. However, the microbial metabolic …