Quantitative proteomics based on 2D electrophoresis (2-DE) coupled with peptide mass
fingerprinting is still one of the most widely used quantitative proteomics approaches in …

Electrophoretic separations of proteins are widely used in proteomic analyses, and rely
heavily on SDS electrophoresis. This mode of separation is almost exclusively used when a …

Low levels of reactive oxygen and nitrogen species (ROS and RNS) produced by the
mitochondrial respiratory chain and ROS and RNS from other sources act as redox signals …

A pH controlled flow cell device was constructed to allow electrophoretic movement of
charged lipids and membrane associated proteins in supported phospholipid bilayers. The …

Myelin, the multilayered membrane that enwraps and insulates neuronal axons for fast
signal propagation, is a plasma membrane specialization of oligodendrocytes and Schwann …

Most autoimmune diseases are multifactorial diseases and are caused by the
immunological reaction against a number of autoantigens. Key for understanding …

Regulated secretory organelles are important subcellular structures of living cells that allow
the release in the extracellular space of crucial compounds, such as hormones and …

During the course of sepsis, heart and liver dysfunction occurs in 20-30% of patients. Both
septic cardiomyopathy and septic liver dysfunction have a high mortality and the underlying …

Aquaporin (AQP) 1 belongs to a ubiquitous family of water channel proteins characterized
by sequence similarity and the presence of two NPA (Asp–Pro–Ala) motifs existing in almost …

Multidimensional protein identification technology (MudPIT) is an invaluable approach to
identify proteins at large-scale level. Here, we describe a procedure of investigation to …