Heterotrimeric G-proteins localized in the plasma membrane convey the signals from G-
protein-coupled receptors (GPCRs) to different effectors. At least some types of G-protein α …

Most drug targets are cellular proteins that selectively interact with chemicals administered
to treat diseases. Chemical proteomics, as an interdisciplinary technology that integrates …

Disease specific proteins are highly valuable as clinical biomarkers, which can be used in
early diagnosis, monitoring disease progressions and evaluating therapies. The …

The outer membrane proteins and the surface proteome (surfaceome) of pathogens provide
a potential powerful tool to understand host‐pathogen interactions as well as the …

Mammals are composed of a large number of surface charged cells. The cell structure and
functions in different tissues and organs are different. Through the method of cell …

One major problem in proteomics is the biochemical complexity of living cells. Therefore,
strategies are needed to reduce the number of proteins to a manageable amount, enabling …

Understanding the complex interactions between plants and microbes in the rhizosphere is
vital for improving agricultural productivity and promoting sustainable crop production. To …

Abstract Free Flow Electrophoresis (FFE) is a liquid-based isoelectric focusing method.
Unlike conventional in-gel fractionation of proteins, FFE can resolve proteins in their native …