Catalytic allylic functionalization via π-allyl palladium chemistry
RA Fernandes, JL Nallasivam - Organic & Biomolecular Chemistry, 2019 - pubs.rsc.org
This review highlights the developments in palladium-catalyzed allylic C–H functionalization
from early 2014 to the present date. π-Allylpalladium chemistry emphasizes the research …
from early 2014 to the present date. π-Allylpalladium chemistry emphasizes the research …
Asymmetric α‐Hydroxylation of a Lactone with Vinylogous Pyridone by Using a Guanidine–Urea Bifunctional Organocatalyst: Catalytic Enantioselective Synthesis of a …
T Watanabe, M Odagi, K Furukori… - … –A European Journal, 2014 - Wiley Online Library
We have developed a catalytic asymmetric synthesis of (S)‐4‐ethyl‐6, 6‐(ethylenedioxy)‐7,
8‐dihydro‐4‐hydroxy‐1H‐pyrano [3, 4‐f] indolizine‐3, 10 (4H) dione (5 a), a synthetic …
8‐dihydro‐4‐hydroxy‐1H‐pyrano [3, 4‐f] indolizine‐3, 10 (4H) dione (5 a), a synthetic …
Synthesis of 7‐Triazole‐substituted Camptothecin via Click Chemistry and Evaluation of in vitro Antitumor Activity
L Wang, W Yuan, J Zhang, L Tong… - Chinese Journal of …, 2014 - Wiley Online Library
Camptothecin (CPT) is a natural topoisomerase I inhibitor with powerful antineoplastic
activity against colorectal, breast, lung and ovarian cancers. To discover more potent …
activity against colorectal, breast, lung and ovarian cancers. To discover more potent …
Asymmetric total synthesis of (20S)-Camptothecin using a chiral auxiliary strategy
Q Liu, M Liu, G Huang, F Chen - Tetrahedron, 2019 - Elsevier
An asymmetric eight-step total synthesis of (20S)-camptothecin, starting from the known
compound tert-butyl (2-chloroquinolin-3-yl) methylcarbamate, is described. A Heck reaction …
compound tert-butyl (2-chloroquinolin-3-yl) methylcarbamate, is described. A Heck reaction …
Palladium (II)-catalyzed aerobic intramolecular allylic CH activation for the synthesis of indolines
C Xu, Z Wu, J Chen, F Xie, W Zhang - Tetrahedron, 2017 - Elsevier
A method for the preparation of indolines via palladium-catalyzed aerobic intramolecular
allylic C single bond H activation was developed. Oxygen was successfully used as oxidant …
allylic C single bond H activation was developed. Oxygen was successfully used as oxidant …
Development of Guanidine-Bisurea Bifunctional Organocatalyst Bearing Chirality at the Inner and Outer Sides of the Urea Groups, and Application to Enantioselective …
M Odagi, T Watanabe, K Nagasawa - Symmetry, 2015 - mdpi.com
Pyranoindolizine is a tricyclic structure found in various biologically active compounds, such
as camptothecin (CPT) and its derivatives. In the case of CPTs, the chirality at the α-position …
as camptothecin (CPT) and its derivatives. In the case of CPTs, the chirality at the α-position …
[PDF][PDF] カンプトテシン誘導体の新規合成法の開発
渡邉達也， ワタナベタツヤ - 2014 - tuat.repo.nii.ac.jp
本研究において著者は, 抗腫瘍薬として有用なカンプトテシン (CPT) 誘導体の効率的不斉合成法の
開発を目指し, 合成の鍵ステップである CPT C20 位不斉炭素の構築に取り組んだ. その結果 …
開発を目指し, 合成の鍵ステップである CPT C20 位不斉炭素の構築に取り組んだ. その結果 …