Background Hereditary angioedema (HAE) is a rare disease characterized by
unpredictable, potentially life-threatening attacks, resulting in significant physical and …

Hereditary angioedema type III (HAEIII) is a rare inherited swelling disorder that is
associated with point mutations in the gene encoding the plasma protease factor XII (FXII) …

Hereditary angioedema is a rare genetic disorder caused by deficiency of C1 esterase
inhibitor (C1-INH) and characterized by recurrent episodes of severe swelling that affect the …

Angioedema is defined by non-dependent, non-pitting edema that affects several different
sites and is potentially life-threatening due to laryngeal edema. This narrative review …

Background The treatment of hereditary angioedema (HAE) has undergone dramatic
changes as newer medicines have become available in recent years. Optimal care of these …

Hereditary angioedema (HAE) represents a prototypic disorder in which episodic swelling,
that is, angioedema, is dependent on the generation of bradykinin. In contrast with the …

Plasma prekallikrein is the liver-derived precursor of the trypsin-like serine protease plasma
kallikrein (PK) and circulates in plasma bound to high molecular weight kininogen. The …

Despite its relatively common occurrence and life‐threatening potential, the management of
angioedema in the emergency department (ED) is lacking in terms of a structured approach …

Objective Tooth extractions may trigger clinical symptoms of hereditary angioedema due to
C1 inhibitor deficiency (HAE-C1-INH). The aim of this study was to determine how many …

Binding of negatively charged macromolecules to factor XII induces a conformational
change such that it becomes a substrate for trace amounts of activated factor present in …