A functional abnormality of C1 inhibitor (C1INH) is present in types I and II hereditary
angioedema (HAE), and normal C1INH may be rendered ineffective in the newly described …

Background The inherited deficiency of C1‐inhibitor (C1‐INH), which can be quantitative
(type I) or qualitative (type II), is characterized by recurrent attacks of oedema, and it is …

Hereditary angioedema due to C1 inhibitor (C1 esterase inhibitor) deficiency (types I and II
HAE-C1-INH) is a rare disease that usually presents during childhood or adolescence with …

Hereditary angioedema (HAE) is a disease which is associated with random and often
unpredictable attacks of painful swelling typically affecting the extremities, bowel mucosa …

Hereditary angioedema (HAE) is a rare genetic disorder in which patients experience
sudden onset of swelling in various locations of the body. HAE is associated with …

Hereditary angioedema (HAE) is a rare, potentially life-threatening genetic disorder that
presents with episodic swelling of the skin or mucosal tissue of the upper respiratory and …

In order to overcome limitations of monoclonal antibodies, new protein-based scaffolds have
been designed and evaluated pre-clinically, and some of them are in clinical studies for the …

This study characterizes the kallikrein-kinin system in vitreous from individuals with diabetic
macular edema (DME) and examines mechanisms contributing to retinal thickening and …

Background Approved on-demand treatments for hereditary angioedema attacks need to be
administered parenterally, a route of administration that is associated with delays in …

Hereditary angioedema (HAE) is a rare, chronic, genetic disease that presents with
nonpruritic angioedema of the face, extremities, airway (can be life-threatening) …