Enhancer function underlies regulatory processes by which cells establish patterns of gene
expression. Recent results suggest that many enhancers are specified by particular …

Nutrients can reverse or change epigenetic phenomena such as DNA methylation and
histone modifications, thereby modifying the expression of critical genes associated with …

Diversity in the genetic profile between individuals and specific ethnic groups affects nutrient
requirements, metabolism and response to nutritional and dietary interventions. Indeed …

Breast cancers are highly heterogeneous but can be grouped into subtypes based on
several criteria, including level of expression of certain markers. Claudin-low breast cancer …

DNA methylation is a fundamentally important epigenetic modification of the mammalian
genome that has widespread influences on gene expression. During germ-cell specification …

Nucleic acids carry a wide range of different chemical modifications. In contrast to previous
views that these modifications are static and only play fine-tuning functions, recent research …

This is the 4th edition of a book that was initiated with the annotation of the function of all the
genes in the most commonly studied baculovirus, AcMNPV. It has been almost six years …

The incidence of obesity and overweight has reached epidemic levels in the United States
and developed countries worldwide. Even more alarming is the increasing prevalence of …

Epigenetic inheritance of DNA methylation in mammals requires a multifunctional protein
UHRF1, which is believed to recruit DNMT1 to DNA replication forks through a unique hemi …

DNA methyltransferases (DNMTs) establish and maintain DNA methylation patterns at
specific regions of the genome, thereby contributing to gene regulation. It is becoming …