Characterization of tissue scaffolds using synchrotron radiation microcomputed tomography imaging

X Duan, N Li, X Chen, N Zhu - Tissue Engineering Part C: Methods, 2021 - liebertpub.com
Distinguishing from other traditional imaging, synchrotron radiation microcomputed
tomography (SR-μCT) imaging allows for the visualization of three-dimensional objects of …

Biomaterials combined with cell therapy for treatment of spinal cord injury

Š Kubinová, E Syková - Regenerative medicine, 2012 - Future Medicine
Spinal cord injury (SCI) is a devastating traumatic injury resulting in paralysis or sensory
deficits due to tissue damage and the poor ability of axons to regenerate across the lesion …

Subcutaneous priming of protein-functionalized chitosan scaffolds improves function following spinal cord injury

TR Ham, DD Pukale, M Hamrangsekachaee… - Materials Science and …, 2020 - Elsevier
Strategies using neural stem cells (NSCs) to aid regeneration following spinal cord injury
(SCI) show much promise, but challenges remain regarding implementation and efficacy. In …

Biomaterial and tissue-engineering strategies for the treatment of brain neurodegeneration

B Martinez, PV Peplow - Neural Regeneration Research, 2022 - journals.lww.com
The incidence of neurodegenerative diseases is increasing due to changing age
demographics and the incidence of sports-related traumatic brain injury is tending to …

Increasing capillary diameter and the incorporation of gelatin enhance axon outgrowth in alginate-based anisotropic hydrogels

K Pawar, R Mueller, M Caioni, P Prang, U Bogdahn… - Acta biomaterialia, 2011 - Elsevier
Substantial recovery of function following peripheral and central nervous system (CNS)
injury critically depends on longitudinally directed axon regeneration across the injury site …

Preparation and evaluation of novel nano-bioglass/gelatin conduit for peripheral nerve regeneration

MF Koudehi, AAI Fooladi, K Mansoori… - Journal of Materials …, 2014 - Springer
Peripheral nerves are exposed to physical injuries usually caused by trauma that may lead
to a significant loss of sensory or motor functions and is considered as a serious health …

Axonal tract reconstruction using a tissue-engineered nigrostriatal pathway in a rat model of Parkinson's disease

LA Struzyna, KD Browne, JC Burrell… - International journal of …, 2022 - mdpi.com
Parkinson's disease (PD) affects 1–2% of people over 65, causing significant morbidity
across a progressive disease course. The classic PD motor deficits are caused by the …

Relationship between scaffold channel diameter and number of regenerating axons in the transected rat spinal cord

AJ Krych, GE Rooney, B Chen, TC Schermerhorn… - Acta biomaterialia, 2009 - Elsevier
Regeneration of endogenous axons through a Schwann cell (SC)-seeded scaffold implant
has been demonstrated in the transected rat spinal cord. The formation of a cellular lining in …

Synergistic effect of neural stem cells and olfactory ensheathing cells on repair of adult rat spinal cord injury

G Wang, Q Ao, K Gong, H Zuo, Y Gong… - Cell …, 2010 - journals.sagepub.com
Spinal cord injury (SCI) is a common clinical disease that places a heavy burden on families
and society. Cellular therapy provides a method of giving a supplement of cells lost in the …

Comparison of polymer scaffolds in rat spinal cord: a step toward quantitative assessment of combinatorial approaches to spinal cord repair

BK Chen, AM Knight, NN Madigan, LA Gross… - Biomaterials, 2011 - Elsevier
The transected rat thoracic (T9/10) spinal cord model is a platform for quantitatively
comparing biodegradable polymer scaffolds. Schwann cell-loaded scaffolds constructed …