Zero-order drug delivery: State of the art and future prospects

ML Laracuente, HY Marina, KJ McHugh - Journal of Controlled Release, 2020 - Elsevier
Pharmaceutical drugs are an important part of the global healthcare system, with some
estimates suggesting over 50% of the world's population takes at least one medication per …

Drug release from in situ forming implants and advances in release testing

X Wang, DJ Burgess - Advanced Drug Delivery Reviews, 2021 - Elsevier
In situ forming implants, defined as liquid formulations that generate solid or semisolid
depots following administration, have shown a range of advantages in drug delivery. This …

Complex ophthalmic formulation technologies: advancement and future perspectives

V Srivastava, PS Chary, N Rajana, ER Pardhi… - Journal of Drug Delivery …, 2023 - Elsevier
The eye is a complex part of the body that has various physiological barriers to protect it from
foreign substances. However, changes to these defense mechanisms can cause eye injury …

Poly (lactic‐co‐glycolic acid) devices: Production and applications for sustained protein delivery

PW Lee, JK Pokorski - Wiley Interdisciplinary Reviews …, 2018 - Wiley Online Library
Injectable or implantable poly (lactic‐co‐glycolic acid)(PLGA) devices for the sustained
delivery of proteins have been widely studied and utilized to overcome the necessity of …

Effect of PLGA as a polymeric emulsifier on preparation of hydrophilic protein-loaded solid lipid nanoparticles

SY Xie, SL Wang, BK Zhao, C Han, M Wang… - Colloids and Surfaces B …, 2008 - Elsevier
Most proteins are hydrophilic and poorly encapsulated into the hydrophobic matrix of solid
lipid nanoparticles (SLN). To solve this problem, poly (lactic-co-glycolic acid)(PLGA) was …

An Overview of Scaffolds and Biomaterials for Skin Expansion and Soft Tissue Regeneration: Insights on Zinc and Magnesium as New Potential Key Elements

N Hassan, T Krieg, M Zinser, K Schröder, N Kröger - Polymers, 2023 - mdpi.com
The utilization of materials in medical implants, serving as substitutes for non-functional
biological structures, supporting damaged tissues, or reinforcing active organs, holds …

Mesenchymal stem cells and alginate microcarriers for craniofacial bone tissue engineering: A review

A Saltz, U Kandalam - … of biomedical materials research Part A, 2016 - Wiley Online Library
Craniofacial bone is a complex structure with an intricate anatomical and physiological
architecture. The defects that exist in this region therefore require a precise control of …

Surface Modification of Poly(d,l-Lactic Acid) Scaffolds for Orthopedic Applications: A Biocompatible, Nondestructive Route via Diazonium Chemistry

H Mahjoubi, JM Kinsella, M Murshed… - ACS Applied Materials …, 2014 - ACS Publications
Scaffolds made with synthetic polymers such as polyesters are commonly used in bone
tissue engineering. However, their hydrophobicity and the lack of specific functionalities …

Effect of Polymer Permeability and Solvent Removal Rate on In Situ Forming Implants: Drug Burst Release and Microstructure

X Zhang, L Yang, C Zhang, D Liu, S Meng, W Zhang… - Pharmaceutics, 2019 - mdpi.com
To explore the mechanism of drug release and depot formation of in situ forming implants
(ISFIs), osthole-loaded ISFIs were prepared by dissolving polylactide, poly (lactide-co …

Submicron-sized nanocomposite magnetic-sensitive carriers: controllable organ distribution and biological effects

MV Novoselova, SV German, OA Sindeeva, OA Kulikov… - Polymers, 2019 - mdpi.com
Although new drug delivery systems have been intensely developed in the past decade, no
significant increase in the efficiency of drug delivery by nanostructure carriers has been …