Patterns of prolactin secretion

HR Phillipps, SH Yip, DR Grattan - Molecular and Cellular Endocrinology, 2020 - Elsevier
Prolactin is pleotropic in nature affecting multiple tissues throughout the body. As a
consequence of the broad range of functions, regulation of anterior pituitary prolactin …

Metabolic functions of prolactin: Physiological and pathological aspects

F Lopez‐Vicchi, C De Winne, B Brie… - Journal of …, 2020 - Wiley Online Library
Prolactin is named after its vital role of promoting milk production during lactation, although it
has been implicated in multiple functions within the body, including metabolism and energy …

[HTML][HTML] Semaglutide lowers body weight in rodents via distributed neural pathways

S Gabery, CG Salinas, SJ Paulsen, J Ahnfelt-Rønne… - JCI insight, 2020 - ncbi.nlm.nih.gov
Semaglutide, a glucagon-like peptide 1 (GLP-1) analog, induces weight loss, lowers
glucose levels, and reduces cardiovascular risk in patients with diabetes. Mechanistic …

Prolactin action in the medial preoptic area is necessary for postpartum maternal nursing behavior

RSE Brown, M Aoki, SR Ladyman… - Proceedings of the …, 2017 - National Acad Sciences
Pregnancy hormones, such as prolactin, sensitize neural circuits controlling parental
interactions to induce timely activation of maternal behaviors immediately after parturition …

Meningeal CGRP‐prolactin interaction evokes female‐specific migraine behavior

A Avona, BN Mason, C Burgos‐Vega… - Annals of …, 2021 - Wiley Online Library
Objective Migraine is three times more common in women. CGRP plays a critical role in
migraine pathology and causes female‐specific behavioral responses upon meningeal …

[HTML][HTML] A neuro-hormonal circuit for paternal behavior controlled by a hypothalamic network oscillation

S Stagkourakis, KO Smiley, P Williams, S Kakadellis… - Cell, 2020 - cell.com
Parental behavior is pervasive throughout the animal kingdom and essential for species
survival. However, the relative contribution of the father to offspring care differs markedly …

[HTML][HTML] Hunger and satiety gauge reward sensitivity

RM Cassidy, Q Tong - Frontiers in endocrinology, 2017 - frontiersin.org
Many of the neurocircuits and hormones known to underlie the sensations of hunger and
satiety also substantially alter the activity of the dopaminergic reward system. Much interest …

[HTML][HTML] Prolactin and growth hormone signaling and interlink focused on the mammosomatotroph paradigm: a comprehensive review of the literature

M Araujo-Castro, M Marazuela… - International Journal of …, 2023 - mdpi.com
Prolactin (PRL) and growth hormone (GH) are peptide hormones that bind to the class 1
cytokine receptor superfamily, a highly conserved cell surface class of receptors. Both …

Prolactin action is necessary for parental behavior in male mice

KO Smiley, RSE Brown, DR Grattan - Journal of Neuroscience, 2022 - Soc Neuroscience
Parental care is critical for successful reproduction in mammals. Recent work has implicated
the hormone prolactin in regulating male parental behavior, similar to its established role in …

Acute suppression of LH secretion by prolactin in female mice is mediated by kisspeptin neurons in the arcuate nucleus

RSE Brown, Z Khant Aung, HR Phillipps, Z Barad… - …, 2019 - academic.oup.com
Hyperprolactinemia causes infertility, but the specific mechanism is unknown. It is clear that
elevated prolactin levels suppress pulsatile release of GnRH from the hypothalamus, with a …