[HTML][HTML] The zebrafish as a model to study intestinal inflammation
S Brugman - Developmental & Comparative Immunology, 2016 - Elsevier
Starting out as a model for developmental biology, during the last decade, zebrafish have
also gained the attention of the immunologists and oncologists. Due to its small size, high …
also gained the attention of the immunologists and oncologists. Due to its small size, high …
Modeling inflammation in zebrafish for the development of anti-inflammatory drugs
Y Xie, AH Meijer, MJM Schaaf - Frontiers in cell and developmental …, 2021 - frontiersin.org
Dysregulation of the inflammatory response in humans can lead to various inflammatory
diseases, like asthma and rheumatoid arthritis. The innate branch of the immune system …
diseases, like asthma and rheumatoid arthritis. The innate branch of the immune system …
Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages in zebrafish spinal cord regeneration
TM Tsarouchas, D Wehner, L Cavone, T Munir… - Nature …, 2018 - nature.com
Spinal cord injury leads to a massive response of innate immune cells in non-regenerating
mammals, but also in successfully regenerating zebrafish. However, the role of the immune …
mammals, but also in successfully regenerating zebrafish. However, the role of the immune …
Studying the fate of tumor extracellular vesicles at high spatiotemporal resolution using the zebrafish embryo
Tumor extracellular vesicles (EVs) mediate the communication between tumor and stromal
cells mostly to the benefit of tumor progression. Notably, tumor EVs travel in the …
cells mostly to the benefit of tumor progression. Notably, tumor EVs travel in the …
Inflammatory cytokines in type 2 diabetes mellitus as facilitators of hypercoagulation and abnormal clot formation
Background The global burden of type 2 diabetes mellitus (T2DM), together with the
presence of cardiovascular risk in this population, is reaching pandemic levels. A prominent …
presence of cardiovascular risk in this population, is reaching pandemic levels. A prominent …
Metformin modulates innate immune-mediated inflammation and early progression of NAFLD-associated hepatocellular carcinoma in zebrafish
S de Oliveira, RA Houseright, AL Graves… - Journal of …, 2019 - Elsevier
Background & Aims Non-alcoholic fatty liver disease/non-alcoholic steatohepatitis
(NAFLD/NASH) is an increasing clinical problem associated with progression to …
(NAFLD/NASH) is an increasing clinical problem associated with progression to …
Commensal bacteria‐immunity crosstalk shapes mucosal homeostasis in teleost fish
YY Yu, LG Ding, ZY Huang, HY Xu… - Reviews in …, 2021 - Wiley Online Library
Fish harbour complex and dynamic microbiota in their mucosal surfaces. Due to the vital role
of commensal microbiota in many biological functions including growth enhancement …
of commensal microbiota in many biological functions including growth enhancement …
Mechanisms of fish macrophage antimicrobial immunity
L Grayfer, B Kerimoglu, A Yaparla… - Frontiers in …, 2018 - frontiersin.org
Overcrowding conditions and temperatures shifts regularly manifest in large-scale infections
of farmed fish, resulting in economic losses for the global aquaculture industries. Increased …
of farmed fish, resulting in economic losses for the global aquaculture industries. Increased …
Zebrafish as a preclinical in vivo screening model for nanomedicines
S Sieber, P Grossen, J Bussmann, F Campbell… - Advanced drug delivery …, 2019 - Elsevier
The interactions of nanomedicines with biological environments is heavily influenced by
their physicochemical properties. Formulation design and optimization are therefore key …
their physicochemical properties. Formulation design and optimization are therefore key …
Specific macrophage populations promote both cardiac scar deposition and subsequent resolution in adult zebrafish
Aims A robust inflammatory response to tissue injury is a necessary part of the repair
process but the deposition of scar tissue is a direct downstream consequence of this …
process but the deposition of scar tissue is a direct downstream consequence of this …