Modulation of NF-κB signalling by microbial pathogens
MM Rahman, G McFadden - Nature Reviews Microbiology, 2011 - nature.com
The nuclear factor-κB (NF-κB) family of transcription factors plays a central part in the host
response to infection by microbial pathogens, by orchestrating the innate and acquired host …
response to infection by microbial pathogens, by orchestrating the innate and acquired host …
Identification and utility of innate immune system evasion mechanisms of ASFV
S Correia, S Ventura, RM Parkhouse - Virus research, 2013 - Elsevier
The interferon (IFN) system is an early innate anti-virus host defense mechanism that takes
place shortly after entry of the pathogen and long before the onset of adaptive immunity …
place shortly after entry of the pathogen and long before the onset of adaptive immunity …
Cytosolic-DNA-mediated, STING-dependent proinflammatory gene induction necessitates canonical NF-κB activation through TBK1
T Abe, GN Barber - Journal of virology, 2014 - Am Soc Microbiol
ABSTRACT STING (stimulator of interferon genes) is known to control the induction of innate
immune genes in response to the recognition of cytosolic DNA species, including the …
immune genes in response to the recognition of cytosolic DNA species, including the …
Rift Valley fever virus NSs protein promotes post-transcriptional downregulation of protein kinase PKR and inhibits eIF2α phosphorylation
T Ikegami, K Narayanan, S Won, W Kamitani… - PLoS …, 2009 - journals.plos.org
Rift Valley fever virus (RVFV)(genus Phlebovirus, family Bunyaviridae) is a negative-
stranded RNA virus with a tripartite genome. RVFV is transmitted by mosquitoes and causes …
stranded RNA virus with a tripartite genome. RVFV is transmitted by mosquitoes and causes …
Psychedelics and immunomodulation: novel approaches and therapeutic opportunities
A Szabo - Frontiers in immunology, 2015 - frontiersin.org
Classical psychedelics are psychoactive substances, which, besides their
psychopharmacological activity, have also been shown to exert significant modulatory …
psychopharmacological activity, have also been shown to exert significant modulatory …
Discovery of a novel type of autophagy targeting RNA
Y Fujiwara, A Furuta, H Kikuchi, S Aizawa… - Autophagy, 2013 - Taylor & Francis
Regulated degradation of cellular components by lysosomes is essential to maintain
biological homeostasis. In mammals, three forms of autophagy, macroautophagy …
biological homeostasis. In mammals, three forms of autophagy, macroautophagy …
Deletion of African swine fever virus (ASFV) H240R gene attenuates the virulence of ASFV by enhancing NLRP3-mediated inflammatory responses
L Huang, H Liu, G Ye, X Liu, W Chen, Z Wang… - Journal of …, 2023 - Am Soc Microbiol
African swine fever (ASF) is a highly contagious infectious disease of domestic pigs and wild
boars caused by African swine fever virus (ASFV), with a mortality rate of up to 100%. In …
boars caused by African swine fever virus (ASFV), with a mortality rate of up to 100%. In …
Interplay between interferon-mediated innate immunity and porcine reproductive and respiratory syndrome virus
Innate immunity is the first line of defense against viral infection, and in turn, viruses have
evolved to evade host immune surveillance. As a result, viruses may persist in host and …
evolved to evade host immune surveillance. As a result, viruses may persist in host and …
Hantavirus‐induced immunity in rodent reservoirs and humans
G Schönrich, A Rang, N Lütteke… - Immunological …, 2008 - Wiley Online Library
Hantaviruses are predominantly rodent‐borne pathogens, although recently novel shrew‐
associated hantaviruses were found. Within natural reservoir hosts, hantairuses do not …
associated hantaviruses were found. Within natural reservoir hosts, hantairuses do not …
The immunomodulatory effects of probiotics on respiratory viral infections: A hint for COVID-19 treatment?
Respiratory virus infections are among the most prevalent diseases in humans and
contribute to morbidity and mortality in all age groups. Moreover, since they can evolve fast …
contribute to morbidity and mortality in all age groups. Moreover, since they can evolve fast …