Despite the discovery of the tuberculosis (TB) bacillus over 100 years ago and the
availability of effective drugs for over 50 years, there remain a number of formidable …

Tuberculosis (TB) is still remains the major threat for human health worldwide. Several case-
control, candidate-gene, family studies and genome-wide association studies (GWAS) …

Several susceptibility-associated genetic polymorphisms have been proposed to explain
differential susceptibility to tuberculosis (TB) disease progression in different populations …

We examined the distribution of single nucleotide polymorphisms (SNPs) in nitric oxide
synthase 2A, monocyte chemoattractant protein–1 (MCP-1), regulated on activation, normal …

The importance of host genetic factors in determining susceptibility to tuberculosis (TB) has
been studied extensively using various methods, such as case‐control, candidate gene and …

The historical impression that tuberculosis was an inherited disorder has come full circle and
substantial evidence now exists of the human genetic contribution to susceptibility to …

The components of the innate immune system that are involved in responses to
mycobacteria overlap with those implicated in allergic disorders. Polymorphisms might …

OBJECTIVE: To explore the potential role of vitamin D receptor (VDR) gene and natural-
resistance-associated macrophage protein 1 (NRAMP1) gene polymorphisms in …

Background Natural resistance associated macrophage protein 1 (NRAMP1), encoded by
the SLC11A1 gene, has been described to regulate macrophage activation and be …

The region of conserved synteny on mouse chromosome 11/human 17q11–q21 is known to
carry a susceptibility gene (s) for intramacrophage pathogens. The region is rich in …