BACKGROUND: Polymorphisms in SLC11A1 gene have been extensively studied for an
association with tuberculosis (TB); however, results from replication studies have been …

Natural resistance‐associated macrophage protein (Nramp1) and the vitamin D receptor
(VDR) are central components of the innate and adaptive immunity against Mycobacterium …

Study objectives Pulmonary disease caused by nontuberculous mycobacteria (NTM) may
occur in patients with no underlying lung disease and no known immunodeficiency. The …

Familial risk of tuberculosis (TB) has been recognized for centuries. Largely through studies
of mono-and dizygotic twin concordance rates, studies of families with Mendelian …

Sarcoidosis (SA) is a systemic granulomatous disorder of unknown etiology characterized
by T helper 1-type inflammatory responses at sites of disease with signs of B cell …

SETTING: Despite efforts at disease control, the inci-dence of tuberculosis (TB) remains high
in India. OBJECTIVE: To assess the role of VDR and SLC11A1 gene polymorphisms in the …

Background Host genetic factors are important determinants in tuberculosis (TB). The
SLC11A1 (or NRAMP1) gene has been studied extensively for genetic association with TB …

Polymorphism in SLC11A1 has been implicated in host susceptibility to tuberculosis. We
have studied associations between INT4, D543N, and 3′ UTR polymorphisms of SLC11A1 …

BACKGROUND/PURPOSE: The human homologue of mice natural-resistance-associated
macrophage protein 1 (Nramp 1) gene, NRAMP 1, has been reported to play a role in …

Introduction: Tuberculosis (TB) remains a public health problem: the latest estimate of new
incident cases per year is a staggering 10.4 million. Despite this overwhelming number, the …