A review on progression of epidermal growth factor receptor (EGFR) inhibitors as an efficient approach in cancer targeted therapy

A Ayati, S Moghimi, S Salarinejad, M Safavi… - Bioorganic …, 2020 - Elsevier
The identification of molecular agents inhibiting specific functions in cancer cells
progression is considered as one of the most successful plans in cancer treatment. The …

Lung cancer: current therapies and new targeted treatments

FR Hirsch, GV Scagliotti, JL Mulshine, R Kwon… - The Lancet, 2017 - thelancet.com
Lung cancer is the most frequent cause of cancer-related deaths worldwide. Every year, 1· 8
million people are diagnosed with lung cancer, and 1· 6 million people die as a result of the …

Non–small cell lung cancer, version 3.2022, NCCN clinical practice guidelines in oncology

DS Ettinger, DE Wood, DL Aisner, W Akerley… - Journal of the National …, 2022 - jnccn.org
NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Non–Small Cell
Lung Cancer (NSCLC) provide recommended management for patients with NSCLC …

[HTML][HTML] Lung cancer organoids analyzed on microwell arrays predict drug responses of patients within a week

Y Hu, X Sui, F Song, Y Li, K Li, Z Chen, F Yang… - Nature …, 2021 - nature.com
While the potential of patient-derived organoids (PDOs) to predict patients' responses to anti-
cancer treatments has been well recognized, the lengthy time and the low efficiency in …

[HTML][HTML] First-line nivolumab in stage IV or recurrent non–small-cell lung cancer

DP Carbone, M Reck, L Paz-Ares… - … England Journal of …, 2017 - Mass Medical Soc
Background Nivolumab has been associated with longer overall survival than docetaxel
among patients with previously treated non–small-cell lung cancer (NSCLC). In an open …

[HTML][HTML] Osimertinib or Platinum–Pemetrexed in EGFR T790M–Positive Lung Cancer

TS Mok, YL Wu, MJ Ahn, MC Garassino… - … England Journal of …, 2017 - Mass Medical Soc
Background Osimertinib is an epidermal growth factor receptor tyrosine kinase inhibitor
(EGFR-TKI) that is selective for both EGFR-TKI sensitizing and T790M resistance mutations …

Non–small cell lung cancer, version 5.2017, NCCN clinical practice guidelines in oncology

DS Ettinger, DE Wood, DL Aisner, W Akerley… - Journal of the National …, 2017 - jnccn.org
This selection from the NCCN Guidelines for Non–Small Cell Lung Cancer (NSCLC)
focuses on targeted therapies and immunotherapies for metastatic NSCLC, because …

[HTML][HTML] Non-small cell lung cancer: current treatment and future advances

C Zappa, SA Mousa - Translational lung cancer research, 2016 - ncbi.nlm.nih.gov
Lung cancer has a poor prognosis; over half of people diagnosed with lung cancer die
within one year of diagnosis and the 5-year survival is less than 18%. Non-small cell lung …

Integration of palliative care into standard oncology care: American Society of Clinical Oncology clinical practice guideline update

BR Ferrell, JS Temel, S Temin, ER Alesi… - Journal of Clinical …, 2017 - cdr.lib.unc.edu
Purpose To provide evidence-based recommendations to oncology clinicians, patients,
family and friend caregivers, and palliative care specialists to update the 2012 American …

Systemic therapy for stage IV non–small-cell lung cancer: American Society of Clinical Oncology clinical practice guideline update

N Hanna, D Johnson, S Temin, S Baker Jr… - Journal of Clinical …, 2017 - ascopubs.org
Purpose Provide evidence-based recommendations updating the 2015 ASCO guideline on
systemic therapy for patients with stage IV non–small-cell lung cancer (NSCLC). Methods …