Pre-clinical models of disease have long played important roles in the advancement of new
treatments. However, in traumatic brain injury (TBI), despite the availability of numerous …

Emerging evidence suggests that immune-inflammatory processes are key elements in the
physiopathological events associated with traumatic brain injury (TBI). TBI is followed by T …

Background Multiple lines of evidence suggest possible impairment of the glymphatic
system in amyotrophic lateral sclerosis (ALS). To investigate this, we used in vivo magnetic …

A history of mild traumatic brain injury (mTBI) is linked to a number of chronic neurological
conditions, however there is still much unknown about the underlying mechanisms. To …

The microbes that colonize the small and large intestines, known as the gut microbiome,
play an integral role in optimal brain development and function. The gut microbiome is a vital …

The gastrointestinal microbiome has emerged as a key player in regulating brain and
behaviour. This has led to the strategy of targeting the gut microbiota to ameliorate disorders …

Mild traumatic brain injury (mTBI) involves damage to the cerebrovascular system. Vascular
endothelial growth factor-A (VEGF-A) is an important modulator of vascular health and VEGF …

Neurological conditions such as traumatic brain injury, stroke, Parkinson's disease, epilepsy,
multiple sclerosis, and Alzheimer's disease are serious clinical problems that affect millions …

Microglia cells during aging, neurodegeneration and neuroinflammation show different
morphological and transcriptional profiles (related to axonal direction and cell adhesion) …

Traumatic brain injury (TBI) is a leading cause of death and disability all over the world. TBI
leads to (1) an inflammatory response,(2) white matter injuries and (3) neurodegenerative …