Rheumatoid arthritis (RA) is a chronic, autoimmune pathology characterized by persistent
synovial inflammation and gradually advancing bone destruction. Matrix metalloproteinases …

Alzheimer's disease (AD) is a progressive neurodegenerative disease mostly affecting the
elderly population. It is characterized by cognitive decline that occurs due to impaired …

Regulating macrophage activation precisely is crucial in treating chronic inflammation in
osteoarthritis (OA). However, the stable pro-inflammatory state and deep distribution of …

Precision medicine and personalized medicine are two approaches to healthcare that aim to
tailor medical treatments and interventions to individual patients. These approaches are …

RNA interference (RNAi) therapeutics are an emerging class of medicines that selectively
target mRNA transcripts to silence protein production and combat disease. Despite the …

This study aimed to investigate the glycan structural changes that occur before histological
degeneration in osteoarthritis (OA) and to determine the mechanism by which these glycan …

Rheumatoid arthritis (RA) is a chronic inflammatory condition known for its irreversible
destructive impact on the joints. Chondrocytes play a pivotal role in the production and …

Osteoarthritis (OA) is a widespread joint disease that affects millions of people worldwide.
Conventional treatments for OA, including non-steroidal anti-inflammatory drugs (NSAIDs) …

Osteoarthritis (OA) is a progressive and irreversible degenerative joint disease that is
characterized by cartilage destruction, osteophyte formation, subchondral bone remodeling …

Osteoarthritis (OA) is a degenerative bone disease characterized by inflammation as a
primary pathology and currently lacks therapeutic interventions to impede its progression …