Type 2 diabetes (T2D) and Alzheimer's diseases (AD) represent major health issues that
have reached alarming levels in the last decades. Although growing evidence demonstrates …

Protein lipidation is a common post-translational modification of proteins that plays an
important role in human physiology and pathology. One form of protein lipidation, S …

Parkinson's disease (PD) is the second most common neurodegenerative disease which is
still incurable. Sea cucumber-derived compounds have been reported to be promising …

Introduction Repetitive transcranial magnetic stimulation (rTMS) is a clinically useful therapy
for depression. However, the effects of rTMS on the metabolism of fatty acids (FAs) and the …

The brain, one of the most resilient organs of the body is highly enriched in lipid content,
suggesting the essential role of lipids in brain physiological activities. Lipids constitute an …

Background Preclinical studies highlight the importance of endogenous cannabinoids
(endocannabinoids; eCBs) in neurodegeneration. Yet, prior observational studies focused …

Long-term cognitive dysfunction, or “chemobrain”, has been observed in cancer patients
treated with chemotherapy. Mitoxantrone (MTX) is a topoisomerase II inhibitor that binds and …

Neurodegenerative diseases (NDs) are characterized by a progressive deterioration of
neuronal function, leading to motor and cognitive damage in patients. Astrocytes are …

Excessive accumulation and release of fatty acids (FAs) in adipose and non-adipose tissue
are characteristic of obesity and are associated with the leading causes of death worldwide …

Secondary metabolites are hidden gems in mushrooms. Understanding these secondary
metabolites' biological and pharmacological effects can be aided by identifying them. The …