Fluorine in pharmaceutical industry: fluorine-containing drugs introduced to the market in the last decade (2001–2011)

J Wang, M Sánchez-Roselló, JL Aceña… - Chemical …, 2014 - ACS Publications
1.1. Brief Historical Overview As expected from the fluorine position on the periodic table of
elements, it possesses some extreme properties, in particular, ultimate electronegativity and …

Risk of premature atherosclerosis and ischemic heart disease associated with HIV infection and antiretroviral therapy

L Calza, R Manfredi, D Pocaterra, F Chiodo - Journal of Infection, 2008 - Elsevier
The use of new potent protease inhibitor-based antiretroviral therapies in patients with
human immunodeficiency virus (HIV) infection has been increasingly associated with …

Meta-analysis of the cholesterol-lowering effect of ezetimibe added to ongoing statin therapy

DP Mikhailidis, GC Sibbring… - … medical research and …, 2007 - Taylor & Francis
Objective: To review and analyse the evidence for the cholesterol-lowering effect of
ezetimibe in adult patients with hypercholesterolaemia who are not at low-density …

Effects of hesperidin on the progression of hypercholesterolemia and fatty liver induced by high-cholesterol diet in rats

X Wang, J Hasegawa, Y Kitamura, Z Wang… - Journal of …, 2011 - jstage.jst.go.jp
The protective effects of hesperidin against hypercholesterolemia and fatty liver were
examined in male Wistar rats fed a high-cholesterol diet for 12 weeks. Compared with a …

Effects of polydatin from Polygonum cuspidatum on lipid profile in hyperlipidemic rabbits

WW Xing, JZ Wu, M Jia, J Du, H Zhang… - Biomedicine & …, 2009 - Elsevier
Hyperlipidemia is one of the vital coronary risk factors and is positively related to morbidity
and mortality of coronary heart disease. There are numerous herbal medicines which are …

Lipid-altering efficacy of the ezetimibe/simvastatin single tablet versus rosuvastatin in hypercholesterolemic patients

AL Catapano, MH Davidson… - … medical research and …, 2006 - Taylor & Francis
Objective: To assess the lipid-altering efficacy and safety of ezetimibe/simvastatin single
tablet product compared with rosuvastatin at the approved usual starting, next highest, and …

Persistence with statins and onset of rheumatoid arthritis: a population-based cohort study

G Chodick, H Amital, Y Shalem, E Kokia… - PLoS …, 2010 - journals.plos.org
Background The beneficial effects of statins in rheumatoid arthritis (RA) have been
suggested previously, but it is unclear whether statins may prevent its development. The aim …

Improved intestinal lymphatic drug targeting via phospholipid complex-loaded nanolipospheres of rosuvastatin calcium

S Beg, K Raza, R Kumar, R Chadha, OP Katare… - RSC …, 2016 - pubs.rsc.org
The present work describes the systematic development and characterization of
nanolipospheres (NLPs) loaded with phospholipid complex of rosuvastatin for enhanced …

Rosuvastatin 5 and 10 mg/d: a pilot study of the effects in hypercholesterolemic adults unable to tolerate other statins and reach LDL cholesterol goals with nonstatin …

CJ Glueck, D Aregawi, M Agloria, Q Khalil… - Clinical …, 2006 - Elsevier
BACKGROUND:: Patients with high levels of low-density lipoprotein cholesterol (LDL-C)
might not tolerate 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (“statins”) …

Pharmacokinetics and pharmacodynamics of combined use of lopinavir/ritonavir and rosuvastatin in HIV-infected patients

M Van Der Lee, R Sankatsing, E Schippers… - Antiviral …, 2007 - journals.sagepub.com
Background Lopinavir/ritonavir-containing antiretro-viral therapy can cause hyperlipidaemia.
However, most statins are contraindicated due to drug-drug interactions. Rosuvastatin …