The stability of mRNA is one of the key factors governing the regulation of eukaryotic gene
expression and function. Human antigen R (HuR) is an RNA-binding protein that regulates …

Hu-antigen R (HuR) is an RNA-binding protein that regulates the stability, translation, and
nucleus-to-cytoplasm translocation of target mRNAs. The aim of the present review was to …

The RNA-binding protein (RBP) HuR is one of the most widely studied regulators of the
eukaryotic posttranscriptional gene expression and it plays a physiological role in mediating …

Abstract Poly (ADP-ribosyl) ation (PARylation) is an important post-translational modification
mainly catalyzed by poly-ADP-ribose polymerase 1 (PARP1). In addition to having important …

Human antigen R (HuR) is a 32 kDa protein with 3 RNA Recognition Motifs (RRMs), which
bind to Adenylate and uridylate Rich Elements (AREs) of mRNAs. Whereas the N-terminal …

Among primary brain cancers, gliomas are the most deadly and most refractory to current
treatment modalities. Previous reports overwhelmingly support the role of the RNA-binding …

Forkhead box, class O (FOXO) transcription factors are major regulators of diverse cellular
processes, including fuel metabolism, oxidative stress response and redox signalling, cell …

The human antigen R (HuR) is an RNA-binding protein known to modulate the expression of
target mRNA coding for proteins involved in inflammation, tumorigenesis, and stress …

Simple Summary Hepatobiliary tumors are a group of primary malignancies encompassing
the liver, the intra-and extra-hepatic biliary tracts, and the gall bladder. Within the liver …

AU‐rich elements (ARE) exist in the 3′‐untranslated regions of the mRNA transcribed from
cell growth‐related genes such as proto‐oncogenes, cyclin‐related genes, and growth …