[HTML][HTML] Piezo1 channels as force sensors in mechanical force-related chronic inflammation

H Liu, J Hu, Q Zheng, X Feng, F Zhan, X Wang… - Frontiers in …, 2022 - frontiersin.org
Mechanical damage is one of the predisposing factors of inflammation, and it runs through
the entire inflammatory pathological process. Repeated or persistent damaging mechanical …

[HTML][HTML] Acinetobacter baumannii: An Ancient Commensal with Weapons of a Pathogen

M Sarshar, P Behzadi, D Scribano, AT Palamara… - Pathogens, 2021 - mdpi.com
Acinetobacter baumannii is regarded as a life-threatening pathogen associated with
community-acquired and nosocomial infections, mainly pneumonia. The rise in the number …

[HTML][HTML] Mechanosensitive Piezo1 protein as a novel regulator in macrophages and macrophage-mediated inflammatory diseases

Y Tang, C Zhao, Y Zhuang, A Zhong, M Wang… - Frontiers in …, 2023 - frontiersin.org
Macrophages are the most important innate immune cells in humans. They are almost
ubiquitous in peripheral tissues with a large variety of different mechanical milieus …

Piezo1 channels restrain ILC2s and regulate the development of airway hyperreactivity

BP Hurrell, S Shen, X Li, Y Sakano… - Journal of Experimental …, 2024 - rupress.org
Mechanosensitive ion channels sense force and pressure in immune cells to drive the
inflammatory response in highly mechanical organs. Here, we report that Piezo1 channels …

TLR9 mediates periodontal aging by fostering senescence and inflammaging

E Albuquerque-Souza, KE Crump… - Journal of Dental …, 2022 - journals.sagepub.com
TLR9 is a critical nucleic acid sensing receptor in mediating periodontitis and periodontitis-
associated comorbidities. Emerging evidence implicates TLR9 as a key sensor during …

Aloe-emodin-mediated antimicrobial photodynamic therapy against multidrug-resistant Acinetobacter baumannii: An in vivo study

Y Wang, J Li, S Geng, X Wang, Z Cui, W Ma… - Photodiagnosis and …, 2021 - Elsevier
Background and aim Antimicrobial photodynamic therapy (aPDT) has shown great potential
for treatment of superficial or localized multidrug-resistant (MDR) Acinetobacter baumannii …

The polyamino-isoprenyl potentiator NV716 revives disused antibiotics against Gram-negative bacteria in broth, infected monocytes, or biofilms, by disturbing the …

G Wang, JM Brunel, H Rodriguez-Villalobos… - European journal of …, 2022 - Elsevier
Potentiators can improve antibiotic activity against difficult-to-treat Gram-negative bacteria
like Escherichia coli, Klebsiella pneumoniae or Acinetobacter baumannii. They represent an …

In vivo efficacy of phage cocktails against carbapenem resistance Acinetobacter baumannii in the rat pneumonia model

S Li, B Wei, L Xu, C Cong, B Murtaza, L Wang… - Journal of …, 2024 - Am Soc Microbiol
Acinetobacter baumannii, an opportunistic pathogen, poses a significant threat in intensive
care units, leading to severe nosocomial infections. The rise of multi-drug-resistant strains …

[HTML][HTML] Establishing a prognostic model of ferroptosis-and immune-related signatures in kidney cancer: A study based on TCGA and ICGC databases

Z Han, H Wang, J Long, Y Qiu, XL Xing - Frontiers in Oncology, 2022 - frontiersin.org
Background Kidney cancer (KC) is one of the most challenging cancers due to its delayed
diagnosis and high metastasis rate. The 5-year survival rate of KC patients is less than …

Serum Level of Antibodies Against Novel Acinetobacter Baumannii OmpA-selected Peptides in ICU Staff: Promise for the Future of Vaccine Development

S Paydarfar, MA Abbasi, A Hashemi… - Iranian Journal of …, 2023 - ijaai.tums.ac.ir
Extensively drug-resistant Acinetobacter baumannii is considered one of the most
dangerous threats to global health, requiring novel therapeutic interventions. The outer …