Mechanics, as a key physical factor which affects cell function and tissue regeneration, is
attracting the attention of researchers in the fields of biomaterials, biomechanics, and tissue …

Quantifying small, rapidly evolving forces generated by cells is a major challenge for the
understanding of biomechanics and mechanobiology in health and disease. Traction force …

As cells with aberrant force-generating phenotypes can directly lead to disease, cellular
force-generation mechanisms are high-value targets for new therapies. Here, we show that …

B lymphocytes use B cell receptors (BCRs) to recognize membrane-bound antigens to
further initiate cell spreading and contraction responses during B cell activation. We …

Understanding the principles underlying the self-organization of stem cells into tissues is
fundamental for deciphering human embryo development. Here, we report that, without …

Significance: It has long been hypothesized that naturally occurring electric fields (EFs) aid
wound healing by guiding cell migration. Consequently, the application of EFs has …

Ubiquitin domain‐containing protein 1 (UBTD 1) is highly evolutionary conserved and has
been described to interact with E2 enzymes of the ubiquitin–proteasome system. However …

Traction force microscopy (TFM) is a well‐established technique traditionally used by
biophysicists to quantify the forces adherent biological cells exert on their microenvironment …

Introduction Traction force microscopy (TFM) is a widely used technique to measure cell
contractility on compliant substrates that mimic the stiffness of human tissues. For every step …

Illumination can have adverse effects on live cells. However, many experiments, eg traction
force microscopy, rely on fluorescence microscopy. Current methods to assess undesired …