Developmental consequences of fetal exposure to drugs: what we know and what we still must learn

EJ Ross, DL Graham, KM Money… - …, 2015 - nature.com
Most drugs of abuse easily cross the placenta and can affect fetal brain development. In
utero exposures to drugs thus can have long-lasting implications for brain structure and …

Review of rodent models of attention deficit hyperactivity disorder

SL Regan, MT Williams, CV Vorhees - Neuroscience & Biobehavioral …, 2022 - Elsevier
Attention deficit hyperactivity disorder (ADHD) is a polygenic neurodevelopmental disorder
that affects 8–12% of children and> 4% of adults. Environmental factors are believed to …

Chronic psychosocial stress during pregnancy affects maternal behavior and neuroendocrine function and modulates hypothalamic CRH and nuclear steroid receptor …

SP Zoubovsky, S Hoseus, S Tumukuntala… - Translational …, 2020 - nature.com
Postpartum depression (PPD) affects up to 20% of mothers and has negative consequences
for both mother and child. Although exposure to psychosocial stress during pregnancy and …

Attention and working memory deficits in a perinatal nicotine exposure mouse model

L Zhang, TJ Spencer, J Biederman, PG Bhide - PloS one, 2018 - journals.plos.org
Background Cigarette smoking by pregnant women is associated with a significant increase
in the risk for cognitive disorders in their children. Preclinical models confirm this risk by …

Prenatal cigarette smoke exposure causes hyperactivity and aggressive behavior: role of altered catecholamines and BDNF

C Yochum, S Doherty-Lyon, C Hoffman… - Experimental …, 2014 - Elsevier
Smoking during pregnancy is associated with a variety of untoward effects on the offspring.
However, recent epidemiological studies have brought into question whether the …

Neurobehavioral abnormalities following prenatal psychosocial stress are differentially modulated by maternal environment

SP Zoubovsky, MT Williams, S Hoseus… - Translational …, 2022 - nature.com
Prenatal stress (PS) is associated with increased vulnerability to affective disorders.
Transplacental glucocorticoid passage and stress-induced maternal environment alterations …

Astaxanthin attenuates environmental tobacco smoke-induced cognitive deficits: a critical role of p38 MAPK

X Yang, AL Guo, YP Pang, XJ Cheng, T Xu, XR Li, J Liu… - Marine Drugs, 2019 - mdpi.com
Increasing evidence indicates that environmental tobacco smoke (ETS) impairs cognitive
function and induces oxidative stress in the brain. Recently, astaxanthin (ATX), a marine …

Cognitive and behavioral impairments evoked by low-level exposure to tobacco smoke components: comparison with nicotine alone

BJ Hall, M Cauley, DA Burke, A Kiany… - Toxicological …, 2016 - academic.oup.com
Active maternal smoking has adverse effects on neurobehavioral development of the
offspring, with nicotine (Nic) providing much of the underlying causative mechanism. To …

Prenatal electronic cigarette exposure decreases brain glucose utilization and worsens outcome in offspring hypoxic–ischemic brain injury

AE Sifat, S Nozohouri, H Villalba… - Journal of …, 2020 - Wiley Online Library
It has been shown that prenatal nicotine and tobacco smoke exposure can cause different
neurobehavioral disorders in the offspring. We hypothesize that prenatal exposure to …

Prenatal nicotine exposure decreases the release of dopamine in the medial frontal cortex and induces atomoxetine-responsive neurobehavioral deficits in mice

T Alkam, T Mamiya, N Kimura, A Yoshida, D Kihara… - …, 2017 - Springer
Increased risk of attention-deficit/hyperactivity disorder (AD/HD) is partly associated with the
early developmental exposure to nicotine in tobacco smoke. Emerging reports link tobacco …