[HTML][HTML] Neuroimaging of mouse models of Alzheimer's disease

A Jullienne, MV Trinh, A Obenaus - Biomedicines, 2022 - mdpi.com
Magnetic resonance imaging (MRI) and positron emission tomography (PET) have made
great strides in the diagnosis and our understanding of Alzheimer's Disease (AD). Despite …

[HTML][HTML] N-truncated Aβ starting at position four—biochemical features, preclinical models, and potential as drug target in Alzheimer's disease

TA Bayer - Frontiers in Aging Neuroscience, 2021 - frontiersin.org
The discussion of whether amyloid plaque Aβ is a valid drug target to fight Alzheimer's
disease (AD) has been a matter of scientific dispute for decades. This question can only be …

[HTML][HTML] Search strategy analysis of Tg4-42 Alzheimer Mice in the Morris Water Maze reveals early spatial navigation deficits

N Curdt, FW Schmitt, C Bouter, T Iseni, HC Weile… - Scientific Reports, 2022 - nature.com
Spatial disorientation is one of the earliest symptoms in Alzheimer's disease and allocentric
deficits can already be detected in the asymptomatic preclinical stages of the disease. The …

[HTML][HTML] A combination of caffeine supplementation and enriched environment in an Alzheimer's disease mouse model

M Stazi, S Zampar, HW Klafki, T Meyer… - International Journal of …, 2023 - mdpi.com
A variety of factors has been associated with healthy brain aging, and epidemiological
studies suggest that physical activity and nutritional supplements such as caffeine may …

Small RNA Sequencing in the Tg4–42 Mouse Model Suggests the Involvement of snoRNAs in the Etiology of Alzheimer's Disease

CT Lio, T Kacprowski, M Klaedtke… - Journal of …, 2022 - content.iospress.com
Background: The Tg4-42 mouse model for sporadic Alzheimer's disease (AD) has unique
features, as the neuronal expression of wild type N-truncated Aß4–42 induces an AD-typical …

TAC1 Gene Therapy in the Gut to Reduce Long-Term Memory Loss in Tg4-42 Alzheimer Diseased Mice: A Research Proposal

T Pereira - Undergraduate Research in Natural and Clinical …, 2023 - urncst.com
Alzheimer's disease (AD) is a neurodegenerative disorder that mainly affects a large
percentage of the older adult population. AD can cause many problems, most notably long …

[PDF][PDF] Neuroimaging of Mouse Models of Alzheimer's Disease. Biomedicines 2022, 10, 305

A Jullienne, MV Trinh, A Obenaus - 2022 - academia.edu
Magnetic resonance imaging (MRI) and positron emission tomography (PET) have made
great strides in the diagnosis and our understanding of Alzheimer's Disease (AD). Despite …

WIN-55,212-2-Therapie in einem Modell für die sporadische Alzheimer Erkrankung

FW Ott - 2022 - ediss.uni-goettingen.de
Die Erkrankung wurde erstmals 1907 von dem Psychiater und Neuropathologen Alois
Alzheimer beschrieben und ist mangels einer kausaler Therapiemöglichkeit Gegenstand …

[引用][C] WIN-55,212-2-Therapie in einem Modell für die sporadische Alzheimer Erkrankung

FW Ott