Capturing the environment of the Clostridioides difficile infection cycle

MK Schnizlein, VB Young - Nature Reviews Gastroenterology & …, 2022 - nature.com
Clostridioides difficile (formerly Clostridium difficile) infection is a substantial health and
economic burden worldwide. Great strides have been made over the past several years in …

Ridinilazole: a novel, narrow‐spectrum antimicrobial agent targeting Clostridium (Clostridioides) difficile

DA Collins, TV Riley - Letters in applied microbiology, 2022 - academic.oup.com
Clostridium (Clostridioides) difficile infection (CDI) remains an urgent threat to patients in
health systems worldwide. Recurrent CDI occurs in up to 30% of cases due to sustained …

Make It Less difficile: Understanding Genetic Evolution and Global Spread of Clostridioides difficile

M Mengoli, M Barone, M Fabbrini, F D'Amico, P Brigidi… - Genes, 2022 - mdpi.com
Clostridioides difficile is an obligate anaerobic pathogen among the most common causes of
healthcare-associated infections. It poses a global threat due to the clinical outcomes of …

Genomic Insights into Virulence Factors and Multi-Drug Resistance in Clostridium perfringens IRMC2505A

R AlJindan, DM AlEraky, M Farhat, NB Almandil… - Toxins, 2023 - mdpi.com
Clostridium perfringens is a spore-forming, Gram-positive anaerobic pathogen that causes
several disorders in humans and animals. A multidrug-resistant Clostridium strain was …

Spore-Forming Clostridium (Clostridioides) difficile in Wastewater Treatment Plants in Western Australia

JM Chisholm, P Putsathit, TV Riley… - Microbiology …, 2023 - Am Soc Microbiol
There is growing evidence that shows Clostridium (Clostridioides) difficile is a pathogen of
One Health importance with a complex dissemination pathway involving animals, humans …

[HTML][HTML] Matching Clostridioides difficile strains obtained from shoe soles of healthcare workers epidemiologically linked to patients and confirmed by whole-genome …

AC Büchler, M Wicki, R Frei, V Hinic… - Journal of Hospital …, 2022 - Elsevier
Background The source of transmission of Clostridioides difficile in healthcare institutions is
frequently unknown. The aim of this prospective cohort study was to assess the association …

Biogeographic distribution and molecular epidemiology of Clostridioides (Clostridium) difficile in Western Australian soils

K Cautivo-Reyes, DR Knight, D Bowie… - Applied and …, 2023 - Am Soc Microbiol
Clostridioides (Clostridium) difficile is a leading cause of infectious diarrhea in humans and
production animals and can be found in a variety of environmental sources. The prevalence …

A local-scale One Health genomic surveillance of Clostridioides difficile demonstrates highly related strains from humans, canines, and the environment

CHD Williamson, CC Roe, J Terriquez… - Microbial …, 2023 - microbiologyresearch.org
Although infections caused by Clostridioides difficile have historically been attributed to
hospital acquisition, growing evidence supports the role of community acquisition in C …

Environmental contamination with Clostridioides (Clostridium) difficile in Vietnam

PA Khun, LD Phi, HTT Bui, NT Bui… - Journal of applied …, 2023 - academic.oup.com
Aims To investigate the prevalence, molecular type, and antimicrobial susceptibility of
Clostridioides difficile in the environment in Vietnam, where little is known about C. difficile …

Linkage study of surveillance and hospital admission data to investigate Clostridium difficile infection in hospital patients in Perth, Western Australia

DA Collins, S Marcella, M Campbell, TV Riley - Anaerobe, 2022 - Elsevier
Objectives Increasing incidence rates of Clostridium difficile infection (CDI) and outbreaks of
emerging strains have highlighted the need for continuous monitoring and surveillance of …