The effect of polyphenols on kidney disease: Targeting mitochondria

F Ashkar, KS Bhullar, J Wu - Nutrients, 2022 - mdpi.com
Mitochondrial function, including oxidative phosphorylation (OXPHOS), mitochondrial
biogenesis, and mitochondria dynamics, are essential for the maintenance of renal health …

A comprehensive and mechanistic review on protective effects of kaempferol against natural and chemical toxins: Role of NF‐κB inhibition and Nrf2 activation

A Hosseini, A Alipour, V Baradaran Rahimi… - BioFactors, 2023 - Wiley Online Library
Different toxins, including chemicals and natural, can be entered from various routes and
influence human health. Herbal medicines and their active components can attenuate the …

A synopsis of current theories on drug-induced nephrotoxicity

L Dobrek - Life, 2023 - mdpi.com
The overriding goal of the treatment of patients is its effectiveness and safety. However, all
medications currently being used also exert some adverse pharmaceutical reactions, which …

Nephroprotective plant species used in traditional Mayan Medicine for renal-associated diseases

R Castañeda, A Cáceres, SM Cruz, JA Aceituno… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance The prevalence of kidney disease has increased rapidly in
recent years and has emerged as one of the leading causes of mortality worldwide. Natural …

The ameliorative effect of kaempferol against CdCl2- mediated renal damage entails activation of Nrf2 and inhibition of NF-kB

AS Alshehri, AF El-Kott, AE El-Kenawy… - … Science and Pollution …, 2022 - Springer
This study evaluated the nephroprotective effect of kaempferol against cadmium chloride
(CdCl2)-induced nephropathy in rats. It also investigated if activation of Nrf2 is a common …

Harmine and Kaempferol treatment enhances NFATC1 and FOXP3 mediated regulatory T-cells' suppressive capacity in generalized vitiligo

PS Giri, AH Bharti, J Kode, R Begum… - International …, 2023 - Elsevier
Background Generalized vitiligo (GV) is an autoimmune disease characterized by the
progressive loss of melanocytes. Objectives Current study was undertaken to assess in-vitro …

[HTML][HTML] Effect of short-term tacrolimus exposure on rat liver: an insight into serum antioxidant status, liver lipid peroxidation, and inflammation

N Fatima, N Sheikh, AR Satoskar, T Akhtar… - Mediators of …, 2021 - hindawi.com
Tacrolimus (TAC) is an immunosuppressive drug, optimally used for liver, kidney, and heart
transplant to avoid immune rejection. In retrospect, a multitude of studies have reported …

[HTML][HTML] Kaempferol attenuates doxorubicin-mediated nephropathy in rats by activating SIRT1 signaling

RI Alagal, NA AlFaris, GM Alshammari… - Journal of Functional …, 2022 - Elsevier
This study examined if sirtuin-1 (SIRT1) signaling mediates the nephroprotective effect of
kaempferol in doxorubicin (DOX)-treated rats. Rats were divided into control, kaempferol …

Screening models of nephrotoxicity and their molecular mechanism

H Kour, A Singh, P Jaiswal, R Sharma - World Journal of Biology …, 2023 - wjbphs.com
Kidney is among the most vital organs in the anatomy of human body which filters 200 litres
of fluid every 24 hours and has many more function which include regulating acid-base …

Benefits of Green Tea Polyphenols for Kidney Health: A Literature Review

NWS Sari, TE Tallei, BJ Kolondam - Grimsa Journal of Science …, 2023 - journals.grimsa.org
The issue of kidney health has emerged as a global public health concern. Kidneys play a
vital role in eliminating toxic substances and maintaining fluid and chemical balance in the …