Functional lung imaging using hyperpolarized gas MRI

SB Fain, FR Korosec, JH Holmes… - Journal of Magnetic …, 2007 - Wiley Online Library
The noninvasive assessment of lung function using imaging is increasingly of interest for the
study of lung diseases, including chronic obstructive pulmonary disease (COPD) and …

The role of the small airways in the pathophysiology of asthma and chronic obstructive pulmonary disease

M Bonini, OS Usmani - Therapeutic Advances in Respiratory …, 2015 - journals.sagepub.com
Chronic respiratory diseases, such as asthma and chronic obstructive pulmonary disease
(COPD), represent a major social and economic burden for worldwide health systems …

Pulmonary functional imaging: Part 1—state-of-the-art technical and physiologic underpinnings

Y Ohno, JB Seo, G Parraga, KS Lee, WB Gefter… - Radiology, 2021 - pubs.rsna.org
Over the past few decades, pulmonary imaging technologies have advanced from chest
radiography and nuclear medicine methods to high-spatial-resolution or low-dose chest CT …

Assessing and treating small airways disease in asthma and chronic obstructive pulmonary disease

OS Usmani, PJ Barnes - Annals of medicine, 2012 - Taylor & Francis
Asthma and chronic obstructive pulmonary disease (COPD) are chronic inflammatory
disorders of the respiratory tract that are characterized by airflow limitation. They are distinct …

Physiological imaging of the lung: single-photon-emission computed tomography (SPECT)

J Petersson, A Sánchez-Crespo… - Journal of applied …, 2007 - journals.physiology.org
Emission tomography provides three-dimensional, quantitative images of the distribution of
radiotracers used to mark physiological, metabolic, or pathological processes. Quantitative …

Imaging lung perfusion

SR Hopkins, MO Wielpütz… - Journal of Applied …, 2012 - journals.physiology.org
From the first measurements of the distribution of pulmonary blood flow using radioactive
tracers by West and colleagues (J Clin Invest 40: 1–12, 1961) allowing gravitational …

[HTML][HTML] Imaging drug delivery to the lungs: Methods and applications in oncology

F Man, J Tang, M Swedrowska, B Forbes… - Advanced Drug Delivery …, 2023 - Elsevier
Direct delivery to the lung via inhalation is arguably one of the most logical approaches to
treat lung cancer using drugs. However, despite significant efforts and investment in this …

Visualizing lung function with positron emission tomography

RS Harris, DP Schuster - Journal of applied physiology, 2007 - journals.physiology.org
Positron emission tomography (PET) provides three-dimensional images of the distributions
of radionuclides that have been inhaled or injected into the lungs. By using radionuclides …

[HTML][HTML] Ventilation/perfusion relationships and gas exchange: measurement approaches

SR Hopkins - Comprehensive Physiology, 2020 - ncbi.nlm.nih.gov
Abstract Ventilation-perfusion (VA/Q) matching, the regional matching of the flow of fresh gas
to flow of deoxygenated capillary blood, is the most important mechanism affecting the …

[HTML][HTML] Contrast-enhanced CT-and MRI-based perfusion assessment for pulmonary diseases: basics and clinical applications

Y Ohno, H Koyama, HY Lee, S Miura… - Diagnostic and …, 2016 - ncbi.nlm.nih.gov
Assessment of regional pulmonary perfusion as well as nodule and tumor perfusions in
various pulmonary diseases are currently performed by means of nuclear medicine studies …