The role of the locus coeruleus in the generation of pathological anxiety

LS Morris, JG McCall, DS Charney… - Brain and …, 2020 - journals.sagepub.com
This review aims to synthesise a large pre-clinical and clinical literature related to a
hypothesised role of the locus coeruleus norepinephrine system in responses to acute and …

[HTML][HTML] The impact of anxiety upon cognition: perspectives from human threat of shock studies

OJ Robinson, K Vytal, BR Cornwell… - Frontiers in human …, 2013 - frontiersin.org
Anxiety disorders constitute a sizeable worldwide health burden with profound social and
economic consequences. The symptoms are wide-ranging; from hyperarousal to difficulties …

Basic emotions, natural kinds, emotion schemas, and a new paradigm

CE Izard - Perspectives on psychological science, 2007 - journals.sagepub.com
Research on emotion flourishes in many disciplines and specialties, yet experts cannot
agree on its definition. Theorists and researchers use the term emotion in ways that imply …

The adaptive threat bias in anxiety: amygdala–dorsomedial prefrontal cortex coupling and aversive amplification

OJ Robinson, DR Charney, C Overstreet, K Vytal… - Neuroimage, 2012 - Elsevier
Functionally, anxiety serves to increase vigilance towards aversive stimuli and improve the
ability to detect and avoid danger. We have recently shown, for instance, that anxiety …

Top–down modulation of prepulse inhibition of the startle reflex in humans and rats

L Li, Y Du, N Li, X Wu, Y Wu - Neuroscience & Biobehavioral Reviews, 2009 - Elsevier
Prepulse inhibition (PPI) is the attenuation of the startle reflex when the sudden intense
startling stimulus is shortly preceded by a weaker, non-startling sensory stimulus (prepulse) …

The preservation of two infant temperaments into adolescence

J Kagan, N Snidman, V Kahn, S Towsley… - Monographs of the …, 2007 - JSTOR
This Monograph reports theoretically relevant behavioral, biological, and self-report
assessments of a sample of 14-17-year-olds who had been classified into one of four …

[HTML][HTML] The impact of induced anxiety on response inhibition

OJ Robinson, M Krimsky, C Grillon - Frontiers in Human …, 2013 - frontiersin.org
Anxiety has wide reaching effects on cognition; evidenced most prominently by the
“difficulties concentrating” seen in anxiety disorders, and by adaptive harm-avoidant …

[HTML][HTML] Withdrawal-associated increases and decreases in functional neural connectivity associated with altered emotional regulation in alcoholism

OG O'daly, L Trick, J Scaife, J Marshall, D Ball… - …, 2012 - nature.com
Alcoholic patients who have undergone multiple detoxifications/relapses show altered
processing of emotional signals. We performed functional magnetic resonance imaging …

The unpredictive brain under threat: a neurocomputational account of anxious hypervigilance

BR Cornwell, MI Garrido, C Overstreet, DS Pine… - Biological …, 2017 - Elsevier
Background Anxious hypervigilance is marked by sensitized sensory-perceptual processes
and attentional biases to potential danger cues in the environment. How this is realized at …

[HTML][HTML] Modeling trait anxiety: from computational processes to personality

JG Raymond, JD Steele, P Seriès - Frontiers in psychiatry, 2017 - frontiersin.org
Computational methods are increasingly being applied to the study of psychiatric disorders.
Often, this involves fitting models to the behavior of individuals with subclinical character …