Methods for modulating skeletal remodeling and patterning by modulating SHN2 activity, SHN3 activity, or SHN2 and SHN3 activity in combination

LH Glimcher, DC Jones, M Wein - US Patent 9,745,589, 2017 - Google Patents
US9745589B2 - Methods for modulating skeletal remodeling and patterning by modulating SHN2
activity, SHN3 activity, or SHN2 and SHN3 activity in combination - Google Patents …

Method for identifying histone tail proteolysis

W An, K Kim - US Patent 10,761,088, 2020 - Google Patents
Although limited proteolysis of the histone H3 N-terminal tail (H3NT) is frequently observed
during mammalian differentiation, the specific genomic sites targeted for H3NT proteolysis …

Composition for reducing senescence of cell or subject comprising smurf2 inhibitor and use thereof

K Choi, J Park, K Hyuntae - US Patent 9,951,336, 2018 - Google Patents
A composition for reducing a level of senescence of a cell or subject, a method of reducing a
level of senescence in a cell or subject by using the composition, and a method of …