Bicyclic nucleosides and conformational restriction of oligonucleotides

M Meldgaard, J Wengel - Journal of the Chemical Society, Perkin …, 2000 - pubs.rsc.org
Bicyclic nucleosides and conformational restriction of oligonucleotides - Journal of the Chemical
Society, Perkin Transactions 1 (RSC Publishing) DOI:10.1039/B000114G Royal Society of …

The eight stereoisomers of LNA (locked nucleic acid): a remarkable family of strong RNA binding molecules

VK Rajwanshi, AE Håkansson… - Angewandte …, 2000 - Wiley Online Library
1724 WILEY-VCH Verlag GmbH, D-69451 Weinheim, 2000 0044-8249/00/11209-1724
$17.50+. 50/0 Angew. Chem. 2000, 112, Nr. 9 towards both complementary DNA (ΔTm 3.08 …

Metal Incorporation into and Dimerization of M3E4 Clusters (M=Mo, W; E=S, Se) in Supramolecular Assemblies with Cucurbituril: A Molecular Model of Intercalation

MN Sokolov, AV Virovets, DN Dybtsev… - Angewandte Chemie …, 2000 - Wiley Online Library
Structural models for the incorporation of metal atoms into layered dichalcogenides, ME 2,
are provided by two series of isostructural hybrid organic–inorganic supramolecular …

Synthesis of Abasic Locked Nucleic Acid and Two seco-LNA Derivatives and Evaluation of Their Hybridization Properties Compared with Their More Flexible DNA …

L Kværnø, R Kumar, BM Dahl, CE Olsen… - The Journal of Organic …, 2000 - ACS Publications
To investigate the structural basis of the unique hybridization properties of LNA (locked
nucleic acid) 1 three novel LNA derivatives with modified carbohydrate parts were …

Photochemistry of Substituted Dibenzothiophene Oxides: The Effect of Trapping Groups1

M Nag, WS Jenks - The Journal of Organic Chemistry, 2005 - ACS Publications
Photolyses of dibenzothiophene sulfoxides (DBTOs) with intramolecular trapping
functionalities attached in the 4-position show higher quantum yields of deoxygenation …

Synthesis of bicyclic nucleosides by ring-closing metathesis

J Ravn, P Nielsen - Journal of the Chemical Society, Perkin …, 2001 - pubs.rsc.org
The ring-closing metathesis method is applied in the construction of conformationally
restricted bicyclic nucleosides. From diacetone-D-glucose, the unsaturated bicyclic …

A conformationally locked tricyclic nucleoside. Synthesis, crystal structure and incorporation into oligonucleotides

J Ravn, N Thorup, P Nielsen - Journal of the Chemical Society, Perkin …, 2001 - pubs.rsc.org
A tricyclic nucleoside is synthesised from a bicyclic nucleoside precursor by applying a
stereoselective dihydroxylation, a regioselective tosylation and an intramolecular ether …

α-l-RNA (α-l-ribo Configured RNA): Synthesis and RNA-Selective Hybridization of α-l-RNA/α-l-LNA Chimera

L Keinicke, MD Sørensen, J Wengel - Bioorganic & medicinal chemistry …, 2002 - Elsevier
Synthesis of the novel α-l-ribofuranosyl phosphoramidite derivative 7 was accomplished via
the α-l-ribofuranosyl thymine nucleoside 4. Amidite 7 was used in automated syntheses of …

Branched oligonucleotides containing bicyclic nucleotides as branching points and DNA or LNA as triplex forming branch

MD Sørensen, M Meldgaard, VK Rajwanshi… - Bioorganic & medicinal …, 2000 - Elsevier
Various Y-shaped branched oligonucleotides containing a 2′-O, 3′-C-ethylene linked or
2′-O, 4′-C-methylene linked bicyclic nucleotide as branching point were synthesized on …

Oligonucleotides Containing Novel 4′‐C‐ or 3′‐C‐(Aminoalkyl)‐Branched Thymidines

HM Pfundheller, T Bryld, CE Olsen… - Helvetica Chimica …, 2000 - Wiley Online Library
The synthesis of four novel 3′‐C‐branched and 4′‐C‐branched nucleosides and their
transformation into the corresponding 3′‐O‐phosphoramidite building blocks for …