A Conformationally Locked Aminomethyl C‐Glycoside and Studies on ItsN‐Pyren‐1‐ylcarbonyl Derivative Inserted into Oligodeoxynucleotides
C Verhagen, T Bryld, M Raunkjær, S Vogel… - 2006 - Wiley Online Library
A new conformationally locked aminomethyl C‐glycoside has been synthesized and
incorporated into oligonucleotides (ONs). The applicability of the monomer in post‐ON …
incorporated into oligonucleotides (ONs). The applicability of the monomer in post‐ON …
Synthesis and RNA-selective hybridization of α-l-ribo-and β-d-lyxo-configured oligonucleotides
G Gaubert, BR Babu, S Vogel, T Bryld, B Vester… - Tetrahedron, 2006 - Elsevier
Three α-l-ribofuranosyl analogues of RNA nucleotides (α-l-RNA analogues) have been
synthesized and incorporated into oligonucleotides using the phosphoramide approach on …
synthesized and incorporated into oligonucleotides using the phosphoramide approach on …
Bicyclic nucleosides; stereoselective dihydroxylation and 2′-deoxygenation
J Ravn, M Freitag, P Nielsen - Organic & biomolecular chemistry, 2003 - pubs.rsc.org
A series of polyhydroxylated bicyclic nucleoside derivatives is approached applying
stereoselective dihydroxylation reactions. Three out of four isomeric and protected products …
stereoselective dihydroxylation reactions. Three out of four isomeric and protected products …
Synthesis of hydroxymethyl branched [3.2. 0] bicyclic nucleosides using a regioselective oxetane ring-formation
NK Christensen, AKL Andersen, TR Schultz… - Organic & biomolecular …, 2003 - pubs.rsc.org
Two [3.2. 0] bicyclic nucleosides, 35 and 34, with one and two hydroxymethyl substituents,
respectively, have been efficiently synthesized. A protected (3′-C-vinyl-β-D-allofuranosyl) …
respectively, have been efficiently synthesized. A protected (3′-C-vinyl-β-D-allofuranosyl) …
N-Methylpiperazinocarbonyl-2′, 3′-BcNA and 4′-C-(N-methylpiperazino) methyl-DNA: introduction of basic functionalities facing the major groove and the minor …
M Raunkjær, T Bryld, J Wengel - Chemical communications, 2003 - pubs.rsc.org
Piperazino-functionalized 2′, 3′-BcNA and 4′-C-hydroxymethyl-DNA are appropriate
molecular architectures for the introduction of basic functionalities facing the major groove …
molecular architectures for the introduction of basic functionalities facing the major groove …
Synthesis and thermal denaturation studies of novel 2′-O, 3′-C-linked bicyclic oligonucleotides with a methoxy or a piperazino group facing the major groove of …
M Raunkjær, MD Sørensen, J Wengel - Organic & Biomolecular …, 2005 - pubs.rsc.org
With the aim of evaluating duplex stabilities of oligonucleotides (ONs) with major groove
facing functionalities, two novel 2′-O, 3′-C-linked bicyclic nucleoside phosphoramidite …
facing functionalities, two novel 2′-O, 3′-C-linked bicyclic nucleoside phosphoramidite …
An ytterbium-catalysed intramolecular aldehyde-ene reaction approach to the guaianolide and pseudoguaianolide diterpenoids: Synthesis of the guaiane skeleton
Thieme E-Journals - Synlett / Full Text DE EN Home Products Journals Books Book Series
Service Library Service Help Contact Portal SYNLETT Full-text search Full-text search Author …
Service Library Service Help Contact Portal SYNLETT Full-text search Full-text search Author …
Tricyclic nucleosides derived from D-glucose. Synthesis and conformational behaviour
P Nielsen, M Petersen, JP Jacobsen - Journal of the Chemical Society …, 2000 - pubs.rsc.org
Two anomeric nucleosides with tricyclic carbohydrate moieties, 3 and 14, are synthesised in
11 steps from diacetone-D-glucose, taking advantage of a stereoselective Grignard reaction …
11 steps from diacetone-D-glucose, taking advantage of a stereoselective Grignard reaction …
Oligodeoxynucleotides Containing Diastereomeric O2′, C3′‐linked Bicyclic Nucleotide Units for Functionalization of the Major Groove of Nucleic Acid Duplexes: A …
M Raunkjær, KF Haselmann… - Journal of carbohydrate …, 2005 - Taylor & Francis
The synthesis and evaluation of a range of piperazino‐derivatized diastereomeric O2′,
C3′‐linked bicyclic nucleotides are described. A new and optimized protocol is presented …
C3′‐linked bicyclic nucleotides are described. A new and optimized protocol is presented …
Synthesis, Structure, and Conformation of 2′, 3′‐Fused Oxathiane and Thiomorpholine Uridines
J Sun, J Wu, H Yang - Helvetica Chimica Acta, 2007 - Wiley Online Library
Abstract The syntheses of two 2′, 3′‐fused bicyclic nucleoside analogues, ie, 1‐[(4aR,
5R, 7R, 7aS)‐hexahydro‐5‐(hydroxymethyl)‐4, 4‐dioxidofuro [3, 4‐b][1, 4] oxathiin‐7‐yl] …
5R, 7R, 7aS)‐hexahydro‐5‐(hydroxymethyl)‐4, 4‐dioxidofuro [3, 4‐b][1, 4] oxathiin‐7‐yl] …