Methods for the chemical synthesis of RNA have been available for almost half century, and
presently, RNA could be chemically synthesized by automated synthesizers, using protected …

The number of publications on oligonucleotides continues to increase, as has the range of
applications. This present review covers a two-year period, and the two major areas of …

This thesis is based on 9 papers dealing with the synthesis, physicochemical and
biochemical properties of two types of chemically modified oligonucleotides which have the …

The interest in modified oligonucleotides continues in this review period, with over 1000
publications cited. A number of new internucleotide linkages have been described, and …

Chemical modifications of natural nucleic acid architecture are well known to be potential for
development of highly functional oligonucleotide analogues applicable to various genomic …