Mechanisms of pathogenesis induced by bovine leukemia virus as a model for human T-cell leukemia virus

Y Aida, H Murakami, M Takahashi… - Frontiers in …, 2013 - frontiersin.org
Bovine leukemia virus (BLV) and human T-cell leukemia virus type 1 (HTLV-1) make up a
unique retrovirus family. Both viruses induce chronic lymphoproliferative diseases with BLV …

Natural history of adult T-cell leukemia/lymphoma and approaches to therapy

GP Taylor, M Matsuoka - Oncogene, 2005 - nature.com
After cell-to-cell transmission, HTLV-I increases its viral genome by de novo infection and
proliferation of infected cells. Proliferation of infected cells is clonal and persistent in vivo …

HTLV-I basic leucine zipper factor gene mRNA supports proliferation of adult T cell leukemia cells

Y Satou, J Yasunaga, M Yoshida… - Proceedings of the …, 2006 - National Acad Sciences
Human T cell leukemia virus type I (HTLV-I) causes adult T cell leukemia (ATL) in 2–5% of
carriers after a long latent period. An HTLV-I encoded protein, Tax, induces proliferation and …

Human T-cell leukemia virus type I (HTLV-1) proviral load and disease progression in asymptomatic HTLV-1 carriers: a nationwide prospective study in Japan

M Iwanaga, T Watanabe, A Utsunomiya… - Blood, The Journal …, 2010 - ashpublications.org
Definitive risk factors for the development of adult T-cell leukemia (ATL) among
asymptomatic human T-cell leukemia virus type I (HTLV-1) carriers remain unclear …

Silencing of human T-cell leukemia virus type I gene transcription by epigenetic mechanisms

Y Taniguchi, K Nosaka, J Yasunaga, M Maeda… - Retrovirology, 2005 - Springer
Background Human T-cell leukemia virus type I (HTLV-I) causes adult T-cell leukemia (ATL)
after a long latent period. Among accessory genes encoded by HTLV-I, the tax gene is …

Human T‐lymphotropic virus type II and neurological disease

A Araujo, WW Hall - Annals of neurology, 2004 - Wiley Online Library
Human T‐lymphotropic virus type I (HTLV‐I) and type II (HTLV‐II) are closely related
retroviruses with similar biological properties and common modes of transmission. HTLV‐I …

Human T-cell leukemia virus type I (HTLV-I) infection and the onset of adult T-cell leukemia (ATL)

M Matsuoka - Retrovirology, 2005 - Springer
The clinical entity of adult T-cell leukemia (ATL) was established around 1977, and human T-
cell leukemia virus type 1 (HTLV-I) was subsequently identified in 1980. In the 25 years …

Identification of aberrantly methylated genes in association with adult T-cell leukemia

J Yasunaga, Y Taniguchi, K Nosaka, M Yoshida… - Cancer research, 2004 - AACR
In this study, we identified 53 aberrantly hypermethylated DNA sequences in adult T-cell
leukemia (ATL) cells using methylated CpG island amplification/representational difference …

Preferential selection of human T-cell leukemia virus type 1 provirus lacking the 5′ long terminal repeat during oncogenesis

M Miyazaki, JI Yasunaga, Y Taniguchi… - Journal of …, 2007 - Am Soc Microbiol
In adult T-cell leukemia (ATL) cells, a defective human T-cell leukemia virus type 1 (HTLV-1)
provirus lacking the 5′ long terminal repeat (LTR), designated type 2 defective provirus, is …

[PDF][PDF] HIV/human T-cell lymphotropic virus coinfection revisited: impact on AIDS progression

C Brites, J Sampalo, A Oliveira - AIDS Rev, 2009 - researchgate.net
Human T-cell lymphotropic viruses type 1 and 2 are retroviruses that share the same routes
of transmission as HIV-1. Since these agents are prevalent simultaneously in different parts …