[HTML][HTML] DICER1 tumor predisposition syndrome: an evolving story initiated with the pleuropulmonary blastoma

IA González, DR Stewart, KAP Schultz, AP Field… - Modern Pathology, 2022 - Elsevier
Abstract DICER1 syndrome (OMIM 606241, 601200) is a rare autosomal dominant familial
tumor predisposition disorder with a heterozygous DICER1 germline mutation. The most …

Genetic landscape of papillary thyroid carcinoma and nuclear architecture: an overview comparing pediatric and adult populations

A Rangel-Pozzo, L Sisdelli, MIV Cordioli, F Vaisman… - Cancers, 2020 - mdpi.com
Simple Summary Papillary thyroid carcinoma (PTC) represents 80–90% of all differentiated
thyroid carcinomas. PTC has a high rate of gene fusions and mutations, which can influence …

Trends in pediatric thyroid cancer incidence in the United States, 1998‐2013

MO Bernier, DR Withrow, A Berrington de Gonzalez… - Cancer, 2019 - Wiley Online Library
Background Pediatric differentiated thyroid cancer (DTC) rates have increased over time in
the United States and worldwide. Improvements in imaging for the diagnosis of DTC have …

Distant metastases from childhood differentiated thyroid carcinoma: clinical course and mutational landscape

M Nies, R Vassilopoulou-Sellin… - The Journal of …, 2021 - academic.oup.com
Context Distant metastases (DM) from childhood differentiated thyroid carcinoma (DTC) are
uncommon and published studies are limited. Objective This work aimed to describe the …

DICER1 Mutations Are Frequent in Adolescent-Onset Papillary Thyroid Carcinoma

JD Wasserman, N Sabbaghian… - The Journal of …, 2018 - academic.oup.com
Context Papillary thyroid carcinoma (PTC) is a common malignancy in adolescence and is
molecularly and clinically distinct from adult PTC. Mutations in the DICER1 gene are …

The use of the Bethesda system for reporting thyroid cytopathology in pediatric thyroid nodules: a meta-analysis

HG Vuong, DGB Chung, LM Ngo, TQ Bui, L Hassell… - Thyroid, 2021 - liebertpub.com
Background: Little is known about the application of the Bethesda System for Reporting
Thyroid Cytopathology (TBSRTC) in pediatric thyroid nodules. This meta-analysis was …

Pediatric thyroid cancer: recent developments

CE Cherella, AJ Wassner - … Practice & Research Clinical Endocrinology & …, 2023 - Elsevier
Thyroid cancer is rare in children but its incidence is increasing. Recent data have clarified
important similarities and differences between thyroid cancers originating in childhood and …

Clinical and molecular characterizations of papillary thyroid cancer in children and young adults: a multicenter retrospective study

K Guo, K Qian, Y Shi, T Sun, L Chen, D Mei, K Dong… - Thyroid, 2021 - liebertpub.com
Background: Papillary thyroid carcinoma (PTC) is a rare malignancy in children and young
adults (CAYA). It often presents with aggressive disease patterns and advanced stages …

Incidence and malignancy rates of indeterminate pediatric thyroid nodules

H Wang, M Mehrad, KA Ely, J Liang… - Cancer …, 2019 - Wiley Online Library
Background The American Thyroid Association guidelines task force currently recommends
definitive thyroidectomy or lobectomy after an indeterminate thyroid biopsy in children. This …

Lung metastasis in children with differentiated thyroid cancer: factors associated with diagnosis and outcomes of therapy

AD Chesover, R Vali, SH Hemmati, JD Wasserman - Thyroid, 2021 - liebertpub.com
Background: Lung metastasis from differentiated thyroid cancer (DTC) in children and young
adults (CAYA) is estimated at 25%, which is 3–4 times higher than in adults. Lung …