Disulfiram (DSF) has been used as an alcoholism drug for 70 years. Recently, it has
attracted increasing attention owing to the distinguished anticancer activity, which can be …

In addition to providing nutrients, food can help prevent and treat certain diseases. In
particular, research on soy products has increased dramatically following their emergence …

A thermosensitive, physically cross-linked injectable hydrogel was formulated for the
effective and sustained delivery of disulfiram (DSF) to the cancer cells as there is no …

Introduction Controlled/extended-release formulations offer numerous benefits over
conventional especially reduced side effects, improved therapeutic outcomes, and high …

The interconnection between tumor metabolism and the immune microenvironment governs
the progression of glioma. It was revealed that the metabolic enzymes ALDH1L1 and PKM2 …

Ginsenosides are the major and key components for ginseng to exert its wide and beneficial
therapeutic efficacy in clinic. Meanwhile, many ginsenosides and their metabolites showed …

The protein family of aldehyde dehydrogenases (ALDH) encompasses nineteen members.
The ALDH1 subfamily consists of enzymes with similar activity, having the capacity to …

Spray drying is an important technology that is fast, simple, reproducible, and scalable. It has
a wide application range, that is, in food, chemicals, and encapsulation of pharmaceuticals …

Safe and effective Cu 2+ supplementation in local lesion is crucial for minimizing toxicity of
DSF-based chemotherapy. Targeted delivery of Cu 2+ appears more promising …

Abstract Digenea simplex (D. simplex), an Egyptian marine red macroalga, contains a
diverse group of phytochemicals with unique bioactivities. At the same time, the synthesis of …