Promoting excellence in end‐of‐life care in ALS
H Mitsumoto, M Bromberg, W Johnston… - Amyotrophic Lateral …, 2005 - Taylor & Francis
The type and quality of end‐of‐life care varies greatly in ALS; the time to initiate end‐of‐life
care is not defined, and decision making is hampered by logistical and financial barriers …
care is not defined, and decision making is hampered by logistical and financial barriers …
The effects of dexpramipexole (KNS-760704) in individuals with amyotrophic lateral sclerosis
M Cudkowicz, ME Bozik, EW Ingersoll, R Miller… - Nature medicine, 2011 - nature.com
Amyotrophic lateral sclerosis (ALS) is characterized by upper and lower motor neuron
dysfunction and loss, rapidly progressive muscle weakness, wasting and death,,. Many …
dysfunction and loss, rapidly progressive muscle weakness, wasting and death,,. Many …
Perampanel for amyotrophic lateral sclerosis: A systematic review and meta-analysis
CWR Turalde, KMC Moalong, AI Espiritu… - Neurological …, 2022 - Springer
Background Amyotrophic lateral sclerosis (ALS) is a fatal and incurable neurodegenerative
disease. There is still no established cost-effective treatment that can improve functional …
disease. There is still no established cost-effective treatment that can improve functional …
Methyl pyruvate rescues mitochondrial damage caused by SIGMAR1 mutation related to amyotrophic lateral sclerosis
Background Amyotrophic lateral sclerosis (ALS) is a disease caused by motor neuron
degeneration. Recently, a novel SIGMAR1 gene variant (p. E102Q) was discovered in some …
degeneration. Recently, a novel SIGMAR1 gene variant (p. E102Q) was discovered in some …
Distributed knowledge in an online patient support community: Authority and discovery
Amyotrophic lateral sclerosis (ALS) is a progressively debilitating neurodegenerative
condition that occurs in adulthood and targets the motor neurons. Social support is crucial to …
condition that occurs in adulthood and targets the motor neurons. Social support is crucial to …
Survival in patients with intermediate or high grade non-Hodgkin's lymphoma: meta-analysis of randomized studies comparing third generation regimens with CHOP
In patients with intermediate or high grade non-Hodgkin lymphoma (NHL), third generation
chemotherapy regimens have been introduced to improve survival in comparison with the …
chemotherapy regimens have been introduced to improve survival in comparison with the …
The costs of amyotrophic lateral sclerosis, according to type of care
IVD Steen, JPVD Berg, E Buskens… - Amyotrophic Lateral …, 2009 - Taylor & Francis
Our objective was to estimate the economic burden of patients with amyotrophic lateral
sclerosis (ALS) and to examine the effect of treatment in a multidisciplinary ALS treatment …
sclerosis (ALS) and to examine the effect of treatment in a multidisciplinary ALS treatment …
Mortality, health, social and economic consequences of amyotrophic lateral sclerosis: a controlled national study
P Jennum, R Ibsen, SW Pedersen, J Kjellberg - Journal of neurology, 2013 - Springer
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that imposes a
great burden on the patient, the patient's family and society. However, we lack information …
great burden on the patient, the patient's family and society. However, we lack information …
Rational discovery of a SOD1 tryptophan oxidation inhibitor with therapeutic potential for amyotrophic lateral sclerosis
Abstract Formation of Cu, Zn superoxide dismutase 1 (SOD1) protein inclusions within motor
neurons is one of the principal characteristics of SOD1-related amyotrophic lateral sclerosis …
neurons is one of the principal characteristics of SOD1-related amyotrophic lateral sclerosis …
Difference in restricted mean survival time for cost-effectiveness analysis using individual patient data meta-analysis: evidence from a case study
Objective In economic evaluation, a commonly used outcome measure for the treatment
effect is the between-arm difference in restricted mean survival time (rmstD). This study …
effect is the between-arm difference in restricted mean survival time (rmstD). This study …