The consumption of a high-fat, low-carbohydrate diet (ketogenic diet) has diverse effects on
health and is expected to have therapeutic value in neurological disorders, metabolic …

Aim To investigate sodium‐glucose cotransporter 2 inhibitor (SGLT2i)‐induced changes in
ketogenic enzymes and transporters in normal and diabetic mice models. Materials and …

Abstract Sodium-glucose cotransporter 2 (SGLT2) inhibitors ameliorate the progression of
diabetic chronic kidney disease, but the mechanisms underlying this nephroprotective effect …

Diabetes is the most common cause of end-stage renal disease, also called kidney failure.
The link between the renal artery receptor angiotensin II type I (AT1R) and endothelin-1 (ET …

Type 2 diabetes mellitus (T2DM) is a chronic disease that has become a global public health
problem. Studies on T2DM prevention and treatment mostly focus on discovering …

The diabetes epidemic and the increasing number of patients with diabetic chronic vascular
complications poses a significant challenge to health care providers. Diabetic kidney …

Autophagy is an intracellular degradation system activated, across species, by starvation.
Although accumulating evidence has shown that mammalian autophagy is involved in …

摘要国家自然科学基金委员会(the Natural Science Foundation of China, NSFC)
作为中国最大的自然科学资助机构, 在促进糖尿病肾病(Diabetic Nephrology, DN) …

Metabolic intermediates serve as precursors for bioactive molecule synthesis, the energy
source for life activities, and signals for environmental adaptation. Ketone bodies are …

Diabetes increases the risk of Cardio-vascular disease (CVD). CVD is more prevalent in
type 2 diabetes (T2D) than type 1 diabetes (T1D), but the mortality risk is higher in T1D than …