Proteomic analysis of liver mitochondria of apolipoprotein E knockout mice treated with metformin
A Stachowicz, M Suski, R Olszanecki, J Madej… - Journal of …, 2012 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is strongly associated with insulin resistance.
Metformin, a widely known anti-diabetic drug, used for patients with type 2 diabetes mellitus …
Metformin, a widely known anti-diabetic drug, used for patients with type 2 diabetes mellitus …
Urinary proteomics for diagnosis and monitoring of diabetic nephropathy
G Currie, C Delles - Current Diabetes Reports, 2016 - Springer
The last decade has seen a surge in publications describing novel biomarkers for early
detection of diabetic nephropathy (DN), but as yet none have outperformed albuminuria in …
detection of diabetic nephropathy (DN), but as yet none have outperformed albuminuria in …
Ketone Body Metabolism in Diabetic Kidney Disease
K Yamahara, M Yasuda-Yamahara, S Kuwagata… - Kidney360, 2024 - journals.lww.com
Ketone bodies have a negative image because of ketoacidosis, one of the acute and serious
complications in diabetes. The negative image persists despite the fact that ketone bodies …
complications in diabetes. The negative image persists despite the fact that ketone bodies …
Proteomics and diabetic nephropathy: what have we learned from a decade of clinical proteomics studies?
M Papale, S Di Paolo, G Vocino, MT Rocchetti… - Journal of …, 2014 - Springer
Diabetic nephropathy (DN) has become the most frequent cause of chronic kidney disease
worldwide due to the constant increase of the incidence of type 2 diabetes mellitus in …
worldwide due to the constant increase of the incidence of type 2 diabetes mellitus in …
Targeted functional investigations guided by integrative proteome network analysis revealed significant perturbations of renal tubular cell functions induced by high …
S Aluksanasuwan, S Khamchun… - …, 2017 - Wiley Online Library
Recently, several studies employed various proteomic approaches to define diabetes‐
induced changes in renal proteins. However, functional significance of those datasets in …
induced changes in renal proteins. However, functional significance of those datasets in …
Stage-specific quantitative changes in renal and urinary proteome during the progression and development of streptozotocin-induced diabetic nephropathy in rats
Diabetic nephropathy (DN) is a microvascular complication associated with diabetes
causing slow deterioration of kidneys leading to end-stage renal disease. Timely …
causing slow deterioration of kidneys leading to end-stage renal disease. Timely …
蛋白质组学在糖尿病中的应用
曹凯淇 - 中国疗养医学, 2015 - cqvip.com
糖尿病是人类慢性病之一, 是目前世界范围内继肿瘤, 心血管疾病后的第三位严重危害人类健康
的非传染性疾病. 糖尿病长期的代谢紊乱常常引起多个系统的损伤, 可导致心, 眼, 肾 …
的非传染性疾病. 糖尿病长期的代谢紊乱常常引起多个系统的损伤, 可导致心, 眼, 肾 …
Proteomics and systems biology for understanding diabetic nephropathy
JM Starkey, RG Tilton - Journal of cardiovascular translational research, 2012 - Springer
Like many diseases, diabetic nephropathy is defined in a histopathological context and
studied using reductionist approaches that attempt to ameliorate structural changes. Novel …
studied using reductionist approaches that attempt to ameliorate structural changes. Novel …
[HTML][HTML] The role of point-of-care 3-hydroxybutyrate testing in patients with type 2 diabetes undergoing coronary angiography
S Vigili de Kreutzenberg, A Avogaro - Journal of endocrinological …, 2017 - Springer
Abstract Purpose Ketone bodies, 3-hydroxybutyrate (3BOHB), and acetoacetate derive from
increased free fatty acid beta-oxidation, thus reflecting marked insulin deprivation with or …
increased free fatty acid beta-oxidation, thus reflecting marked insulin deprivation with or …
Ⅱ 型糖尿病肾病小鼠肾水提物代谢组学研究
毛璇， 张冬娟， 管又飞， 颜贤忠 - 波谱学杂志, 2010 - cqvip.com
应用基于核磁共振的代谢组学方法研究Ⅱ 型糖尿病模型db/db 小鼠已发展到糖尿病肾病时肾脏
代谢表型的变化. 结合偏最小二乘法-判别分析(PLS-DA), 结果显示, 与正常组相比 …
代谢表型的变化. 结合偏最小二乘法-判别分析(PLS-DA), 结果显示, 与正常组相比 …