Like many diseases, diabetic nephropathy is defined in a histopathological context and
studied using reductionist approaches that attempt to ameliorate structural changes. Novel …

目的探讨前列腺素E2 受体1 亚型(EP1) 对转化生长因子-β1 (TGF-β1) 诱导的小鼠肾小球系膜
细胞(MCs) 增殖, 细胞外基质的影响及可能机制. 方法体外原代培养MCs. 采用脂质体 …

In situ profiling of subcellular proteomic networks in primary and living systems, such as
primary cells derived from native tissues or clinic samples, is crucial for the understanding of …

Diabetes is the most common cause of end-stage renal disease, also called kidney failure.
The link between the renal artery receptor angiotensin II type I (AT1R) and endothelin-1 (ET …

TGFβ signaling plays a major role in the reorganization of liver tissue upon injury and is an
important driver of chronic liver disease. This is achieved by a deep impact on a cohort of …

Background: Adjunctive-to-insulin SGLT2 inhibition (SGLT2i) in type 1 diabetes (T1D) has
meaningful metabolic benefits but can increase risk of ketoacidosis. Knowledge gaps …

Proteomics has come a long way from the initial qualitative analysis of proteins present in a
given sample to the large-scale characterization of proteomes, their interactions and …

Que Dña. INMACULADA GALÁN CHILET, Licenciada en Ciencias Biológicas por la
Universitat de València, ha realizado bajo mi dirección en la Fundación de Investigación …

Aim.–To identify the changes of mitochondrial protein expression in diabetic renal
parenchyma and to characterize their molecular functions and biological processes in …