Proteomics and systems biology for understanding diabetic nephropathy
JM Starkey, RG Tilton - Journal of cardiovascular translational research, 2012 - Springer
Like many diseases, diabetic nephropathy is defined in a histopathological context and
studied using reductionist approaches that attempt to ameliorate structural changes. Novel …
studied using reductionist approaches that attempt to ameliorate structural changes. Novel …
前列腺素E2 受体1 亚型在转化生长因子β1 诱导的小鼠系膜细胞损伤中的作用机制
马雯, 徐玉音, 仇芝 - 肾脏病与透析肾移植杂志, 2015 - njcndt.com
目的探讨前列腺素E2 受体1 亚型(EP1) 对转化生长因子-β1 (TGF-β1) 诱导的小鼠肾小球系膜
细胞(MCs) 增殖, 细胞外基质的影响及可能机制. 方法体外原代培养MCs. 采用脂质体 …
细胞(MCs) 增殖, 细胞外基质的影响及可能机制. 方法体外原代培养MCs. 采用脂质体 …
Bioorthogonal Photocatalytic Profiling of Mitochondrial Proteomes from Primary Living Samples
Z Liu, F Guo, Y Zhu, S Qin, Y Hou, F Lin, H Guo… - 2023 - chemrxiv.org
In situ profiling of subcellular proteomic networks in primary and living systems, such as
primary cells derived from native tissues or clinic samples, is crucial for the understanding of …
primary cells derived from native tissues or clinic samples, is crucial for the understanding of …
[PDF][PDF] Metformin Is Associated with the Inhibition of Renal Artery AT1R/ET-1/iNOS Axis in a Rat Model of Diabetic Nephropathy with Suppression of Inflammation and …
Diabetes is the most common cause of end-stage renal disease, also called kidney failure.
The link between the renal artery receptor angiotensin II type I (AT1R) and endothelin-1 (ET …
The link between the renal artery receptor angiotensin II type I (AT1R) and endothelin-1 (ET …
[HTML][HTML] Metabolic Consequences of TGFb Stimulation in CulturedPrimary Mouse Hepatocytes Screened from Transcript Data with ModeScore
A Hoppe, I Ilkavets, S Dooley, HG Holzhütter - Metabolites, 2012 - mdpi.com
TGFβ signaling plays a major role in the reorganization of liver tissue upon injury and is an
important driver of chronic liver disease. This is achieved by a deep impact on a cohort of …
important driver of chronic liver disease. This is achieved by a deep impact on a cohort of …
The Effects of Sodium-Glucose Co-transporter 2 Inhibition on Plasma and Urine Ketones in Type 1 Diabetes
D Scarr - 2022 - search.proquest.com
Background: Adjunctive-to-insulin SGLT2 inhibition (SGLT2i) in type 1 diabetes (T1D) has
meaningful metabolic benefits but can increase risk of ketoacidosis. Knowledge gaps …
meaningful metabolic benefits but can increase risk of ketoacidosis. Knowledge gaps …
Proteomics in the systems-level study of the metabolic syndrome
I Rubio-Aliaga, I Silva-Zolezzi, M Affolter… - A systems biology …, 2014 - Springer
Proteomics has come a long way from the initial qualitative analysis of proteins present in a
given sample to the large-scale characterization of proteomes, their interactions and …
given sample to the large-scale characterization of proteomes, their interactions and …
[PDF][PDF] Identificación de variantes genéticas poco frecuentes y raras en Diabetes mellitus tipo 2 mediante secuenciación de exoma
IG Chilet - 2016 - roderic.uv.es
Que Dña. INMACULADA GALÁN CHILET, Licenciada en Ciencias Biológicas por la
Universitat de València, ha realizado bajo mi dirección en la Fundación de Investigación …
Universitat de València, ha realizado bajo mi dirección en la Fundación de Investigación …
Down-regulation of alpha-2u globulin in renal mitochondria of STZ-induced diabetic rats observed by a proteomic method
SH Sun, SQ Liu, CP Cai, R Cai, L Chen… - Annales d' …, 2012 - Elsevier
Aim.–To identify the changes of mitochondrial protein expression in diabetic renal
parenchyma and to characterize their molecular functions and biological processes in …
parenchyma and to characterize their molecular functions and biological processes in …