Hyperhomocysteinemia/Homocysteinuria is characterized by an increased level of toxic
homocysteine in the plasma. The plasma concentration of homocysteine is 5–15 μmol/L in …

Choline is an essential nutrient, but is also formed by de novo synthesis. Choline and its
derivatives serve as components of structural lipoproteins, blood and membrane lipids, and …

During the fifteen years since the bestselling first edition of Folate in Health and Disease
was published, there have been thousands of new research studies related to folate and its …

Almost 7% of breast cancers are diagnosed among women age 40 years and younger in
Western populations. Clinical outcomes among young women are worse. Early age-of-onset …

Breast cancer is the most frequent type of nonskin malignancy among women worldwide. In
general, conventional cancer treatment options (ie, surgery, radiotherapy, chemotherapy …

Marginal vitamin B6 (B6) deficiency is a widespread global concern. Inadequate B6 levels
have been linked to an increased risk of age-related chronic diseases such as …

Simple Summary While most systematic reviews have focused on the association between
dietary factors and breast cancer incidence, this current study focuses on the association …

Metabolomic fingerprint of breast cancer cells treated with the antidiabetic drug metformin
revealed a significant accumulation of 5-formimino-tetrahydrofolate, one of the …

The evidence regarding the intake of dietary folate, vitamin B6, and vitamin B12 in relation to
mortality in the general population is limited. This study aimed to examine the relationship …

Background Several studies have determined that dietary intake of B vitamins may be
associated with breast cancer risk as a result of interactions between 5, 10 …