The cardiovascular subtleties of testosterone on gender-affirming hormone therapy

JD Santos, JT Oliveira-Neto… - American Journal of …, 2023 - journals.physiology.org
The growing number of people who identify themselves as transgender has gained
increased attention in recent years and will certainly impact personalized clinical practices …

The utility of preclinical models in understanding the bone health of transgender individuals undergoing gender-affirming hormone therapy

VS Venkatesh, T Nie, JD Zajac, M Grossmann… - Current Osteoporosis …, 2023 - Springer
Abstract Purpose of Review To summarise the evidence regarding the effects of gender-
affirming hormone therapy (GAHT) on bone health in transgender people, to identify key …

Similar fertilization rates and preimplantation embryo development among testosterone-treated transgender men and cisgender women

T Israeli, L Preisler, Y Kalma, N Samara, S Levi… - Reproductive …, 2022 - Elsevier
Research question What are the effects of testosterone treatment on oocyte fertilization and
preimplantation embryo development among transgender men who have undergone fertility …

Presence of ovarian stromal aberrations after cessation of testosterone therapy in a transgender mouse model

HM Kinnear, PH Hashim, C Dela Cruz… - Biology of …, 2023 - academic.oup.com
Some transmasculine individuals may be interested in pausing gender-affirming
testosterone therapy and carrying a pregnancy. The ovarian impact of taking and pausing …

Risk assessment of transgender people: development of rodent models mimicking gender-affirming hormone therapies and identification of sex-dimorphic liver genes …

R Tassinari, A Tammaro, G Lori, S Tait, A Martinelli… - Cells, 2023 - mdpi.com
Transgender (TG) describes individuals whose gender identity differs from the social norms.
TG people undergoing gender-affirming hormone therapy (HT) may be considered a sub …

Puberty suppression followed by testosterone therapy does not impair reproductive potential in female mice

P Godiwala, TF Uliasz, KM Lowther, D Kaback… - …, 2023 - academic.oup.com
More adolescents are coming out as transgender each year and are put on puberty blockers
to suppress natal puberty, which is then followed by cross-hormone treatment to achieve …

Reproductive capacity after gender-affirming testosterone therapy

HM Kinnear, MB Moravek - Human Reproduction, 2023 - academic.oup.com
Transgender and nonbinary people with female birth sex may utilize testosterone therapy for
masculinization. Individuals interested in reproduction using their own gametes should be …

Reproductive potential and fertility preservation in transgender and nonbinary individuals

AR Schwartz, MB Moravek - Current Opinion in Obstetrics and …, 2021 - journals.lww.com
Current evidence demonstrates variable effects of gender-affirming hormones on ovarian
and testicular function with potential for detrimental impact on an individual's reproductive …

Impaired in vitro fertilization outcomes following testosterone treatment improve with washout in a mouse model of gender-affirming hormone treatment

AR Schwartz, M Xu, NC Henderson, CD Cruz… - American Journal of …, 2023 - Elsevier
Background The impact of gender-affirming testosterone on fertility is poorly understood,
with ovarian histopathologic studies showing variable results, some with a detrimental effect …

Reversibility of testosterone-induced acyclicity after testosterone cessation in a transgender mouse model

HM Kinnear, PH Hashim, CD Cruz, G Rubenstein… - F&S Science, 2021 - Elsevier
Objective To establish if the cessation of testosterone (T) therapy reverses T-induced
acyclicity in a transgender mouse model that allows for well-defined T cessation timing …