Current updates and future perspectives on the management of renal cell carcinoma
D Singh - Life sciences, 2021 - Elsevier
Renal cell carcinoma (RCC) refers to renal-epithelial cancer, which represents over 90% of
kidney cancer and is a cause for cancer related deaths in the world. Studies suggested …
kidney cancer and is a cause for cancer related deaths in the world. Studies suggested …
Renal progenitors: an evolutionary conserved strategy for kidney regeneration
Following kidney injury, repair can result in functional tissue becoming a patch of cells and
disorganized extracellular matrix—a scar—or it can recapitulate the original tissue …
disorganized extracellular matrix—a scar—or it can recapitulate the original tissue …
The Role of Hypoxia and Cancer Stem Cells in Renal Cell Carcinoma Pathogenesis
A Myszczyszyn, AM Czarnecka, D Matak… - Stem cell reviews and …, 2015 - Springer
The cancer stem cell (CSC) model has recently been approached also in renal cell
carcinoma (RCC). A few populations of putative renal tumor-initiating cells (TICs) were …
carcinoma (RCC). A few populations of putative renal tumor-initiating cells (TICs) were …
Alternative splice variants of DCLK1 mark cancer stem cells, promote self‐renewal and drug‐resistance, and can be targeted to inhibit tumorigenesis in kidney cancer
Y Ge, N Weygant, D Qu, R May… - … journal of cancer, 2018 - Wiley Online Library
Renal cell carcinoma (RCC) is a common and devastating disease characterized by a
hypoxic microenvironment, epithelial‐mesenchymal transition and potent resistance to …
hypoxic microenvironment, epithelial‐mesenchymal transition and potent resistance to …
How much can the tubule regenerate and who does it? An open question
D Lombardi, F Becherucci… - Nephrology Dialysis …, 2016 - academic.oup.com
The tubular compartment of the kidney is the primary site of a wide range of insults that can
result in acute kidney injury (AKI), a condition associated with high mortality and an …
result in acute kidney injury (AKI), a condition associated with high mortality and an …
RBP2 induces stem-like cancer cells by promoting EMT and is a prognostic marker for renal cell carcinoma
D Zhou, V Kannappan, X Chen, J Li, X Leng… - … & molecular medicine, 2016 - nature.com
Renal cell carcinoma (RCC), one of the most common kidney cancers, has a poor
prognosis. Epithelial to mesenchymal transition (EMT) is a hallmark of carcinoma invasion …
prognosis. Epithelial to mesenchymal transition (EMT) is a hallmark of carcinoma invasion …
IL‐8 and CXCR1 expression is associated with cancer stem cell‐like properties of clear cell renal cancer
C Corrò, ME Healy, S Engler… - The Journal of …, 2019 - Wiley Online Library
Recent studies suggest that clear cell renal cell carcinoma (ccRCC) possesses a rare
population of cancer stem cells (CSCs) that might contribute to tumor heterogeneity …
population of cancer stem cells (CSCs) that might contribute to tumor heterogeneity …
Fetal cell carcinogenesis of the thyroid: A modified theory based on recent evidence [My Opinion]
T Takano - Endocrine Journal, 2014 - jstage.jst.go.jp
Thyroid cancer cells were believed to be generated by multi-step carcinogenesis, in which
cancer cells are derived from thyrocytes, via multiple incidences of damage to their genome …
cancer cells are derived from thyrocytes, via multiple incidences of damage to their genome …
Renal cancer stem cells: characterization and targeted therapies
AJ Peired, A Sisti, P Romagnani - Stem cells international, 2016 - Wiley Online Library
Renal cell carcinoma (RCC) is a major neoplasm with high incidence in western countries.
Tumors are heterogeneous and are composed of differentiated cancer cells, stromal cells …
Tumors are heterogeneous and are composed of differentiated cancer cells, stromal cells …
Chronic oxidative stress leads to malignant transformation along with acquisition of stem cell characteristics, and epithelial to mesenchymal transition in human renal …
PKS Mahalingaiah, L Ponnusamy… - Journal of cellular …, 2015 - Wiley Online Library
Oxidative injury to cellular macromolecules has been suggested as a common pathway
shared by multiple etiological factors for kidney cancer. Whether the chronic oxidative stress …
shared by multiple etiological factors for kidney cancer. Whether the chronic oxidative stress …