The molecular basis of self-avoidance

S Lawrence Zipursky, WB Grueber - Annual review of …, 2013 - annualreviews.org
Self-avoidance, the tendency of neurites of the same cell to selectively avoid each other, is a
property of both vertebrate and invertebrate neurons. In Drosophila, self-avoidance is …

Intrinsic and extrinsic mechanisms of dendritic morphogenesis

X Dong, K Shen, HE Bülow - Annual review of physiology, 2015 - annualreviews.org
The complex, branched morphology of dendrites is a cardinal feature of neurons and has
been used as a criterion for cell type identification since the beginning of neurobiology …

A multilevel multimodal circuit enhances action selection in Drosophila

T Ohyama, CM Schneider-Mizell, RD Fetter, JV Aleman… - Nature, 2015 - nature.com
Natural events present multiple types of sensory cues, each detected by a specialized
sensory modality. Combining information from several modalities is essential for the …

Quantitative neuroanatomy for connectomics in Drosophila

CM Schneider-Mizell, S Gerhard, M Longair… - Elife, 2016 - elifesciences.org
Neuronal circuit mapping using electron microscopy demands laborious proofreading or
reconciliation of multiple independent reconstructions. Here, we describe new methods to …

The mechanosensitive ion channel piezo inhibits axon regeneration

Y Song, D Li, O Farrelly, L Miles, F Li, SE Kim, TY Lo… - Neuron, 2019 - cell.com
Neurons exhibit a limited ability of repair. Given that mechanical forces affect neuronal
outgrowth, it is important to investigate whether mechanosensitive ion channels may …

Light-avoidance-mediating photoreceptors tile the Drosophila larval body wall

Y Xiang, Q Yuan, N Vogt, LL Looger, LY Jan, YN Jan - Nature, 2010 - nature.com
Photoreceptors for visual perception, phototaxis or light avoidance are typically clustered in
eyes or related structures such as the Bolwig organ of Drosophila larvae. Unexpectedly, we …

[HTML][HTML] Golgi outposts shape dendrite morphology by functioning as sites of acentrosomal microtubule nucleation in neurons

KM Ori-McKenney, LY Jan, YN Jan - Neuron, 2012 - cell.com
Microtubule nucleation is essential for proper establishment and maintenance of axons and
dendrites. Centrosomes, the primary site of nucleation in most cells, lose their function as …

Nociceptive neurons protect Drosophila larvae from parasitoid wasps

RY Hwang, L Zhong, Y Xu, T Johnson, F Zhang… - Current biology, 2007 - cell.com
Background Natural selection has resulted in a complex and fascinating repertoire of innate
behaviors that are produced by insects. One puzzling example occurs in fruit fly larvae that …

Growing dendrites and axons differ in their reliance on the secretory pathway

B Ye, Y Zhang, W Song, SH Younger, LY Jan, YN Jan - Cell, 2007 - cell.com
Little is known about how the distinct architectures of dendrites and axons are established.
From a genetic screen, we isolated dendritic arbor reduction (dar) mutants with reduced …

[HTML][HTML] Dendrite self-avoidance is controlled by Dscam

BJ Matthews, ME Kim, JJ Flanagan, D Hattori… - Cell, 2007 - cell.com
Dendrites distinguish between sister branches and those of other cells. Self-recognition can
often lead to repulsion, a process termed" self-avoidance." Here we demonstrate that …