[HTML][HTML] Regulatory mechanisms of circular RNAs during human mesenchymal stem cell osteogenic differentiation
Human osteogenic differentiation is a complex and well-orchestrated process which
involves a plethora of molecular players and cellular processes. A growing number of …
involves a plethora of molecular players and cellular processes. A growing number of …
[HTML][HTML] Epigenetic programing of cancer stemness by transcription factors-non-coding RNAs interactions
RKME Alsayed, KSAM Sheikhan, MA Alam… - Seminars in Cancer …, 2023 - Elsevier
Cancer 'stemness' is fundamental to cancer existence. It defines the ability of cancer cells to
indefinitely perpetuate as well as differentiate. Cancer stem cell populations within a …
indefinitely perpetuate as well as differentiate. Cancer stem cell populations within a …
CircPPAP2B controls metastasis of clear cell renal cell carcinoma via HNRNPC-dependent alternative splicing and targeting the miR-182-5p/CYP1B1 axis
Z Zheng, X Zeng, Y Zhu, M Leng, Z Zhang, Q Wang… - Molecular Cancer, 2024 - Springer
Background Renal cell carcinoma (RCC) is one of the most common malignant tumor
worldwide. Metastasis is a leading case of cancer-related deaths of RCC. Circular RNAs …
worldwide. Metastasis is a leading case of cancer-related deaths of RCC. Circular RNAs …
[HTML][HTML] Targeting LRP6: a new strategy for cancer therapy
W Xue, B Zhu, K Zhao, Q Huang, H Luo, Y Shou… - Pharmacological …, 2024 - Elsevier
Targeting specific molecular drivers of tumor growth is a key approach in cancer therapy.
Among these targets, the low-density lipoprotein receptor-related protein 6 (LRP6), a vital …
Among these targets, the low-density lipoprotein receptor-related protein 6 (LRP6), a vital …
[HTML][HTML] Non-coding RNAs in renal cell carcinoma: Implications for drug resistance
Y Liu, H Zhang, Y Fang, D Tang, Z Luo - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Renal cell carcinoma (RCC) represents a malignant tumor of the urinary system. Individuals
with early-stage RCC could be cured by surgical treatment, but a considerable number of …
with early-stage RCC could be cured by surgical treatment, but a considerable number of …
Circular RNAs in renal cell carcinoma: from mechanistic to clinical perspective
C Huang, P Esfani Sarafraz, P Enayati… - Cancer Cell …, 2023 - Springer
CircRNAs, a special type of noncoding RNAs characterized by their stable structure and
unique abilities to form backsplicing loops, have recently attracted the interest of scientists …
unique abilities to form backsplicing loops, have recently attracted the interest of scientists …
Mechanisms of ferroptosis and targeted therapeutic approaches in urological malignancies
W Ma, X Jiang, R Jia, Y Li - Cell Death Discovery, 2024 - nature.com
The prevalence of urological malignancies remains a significant global health concern,
particularly given the challenging prognosis for patients in advanced disease stages …
particularly given the challenging prognosis for patients in advanced disease stages …
An updated database of virus circular RNAs provides new insights into the biogenesis mechanism of the molecule
P Fu, Z Cai, Z Zhang, X Meng… - Emerging Microbes & …, 2023 - Taylor & Francis
Virus circular RNAs (circRNA) have been reported to be extensively expressed and play
important roles in viral infections. Previously we build the first database of virus circRNAs …
important roles in viral infections. Previously we build the first database of virus circRNAs …
The role of E3 ubiquitin ligases and deubiquitinases in bladder cancer development and immunotherapy
X Wang, Y Zhang, Y Wu, H Cheng, X Wang - Frontiers in Immunology, 2023 - frontiersin.org
Bladder cancer is one of the common malignant urothelial tumors. Post-translational
modification (PTMs), including ubiquitination, acetylation, methylation, and phosphorylation …
modification (PTMs), including ubiquitination, acetylation, methylation, and phosphorylation …
CircTENM3 inhibites tumor progression via the miR-558/RUNX3 axis in prostate cancer
L Lu, F Wang, J Chen, C Zhao, S Guo, D Dong… - Journal of Translational …, 2023 - Springer
Abstract Background Prostate cancer (PCa) is currently acknowledged as the second most
widespread cancer among men worldwide. Yet, the lack of dependable diagnostic …
widespread cancer among men worldwide. Yet, the lack of dependable diagnostic …