Vrednotenje zaviralcev imunoproteasoma z elektrofilnim oksatiazolonom

S Očko - 2019 - repozitorij.uni-lj.si
Imunoproteasom je visoko učinkovit proteazni kompleks, ki se pretežno nahaja v celicah
imunskega sistema, kjer sodeluje pri antigenski predstavitvi, uravnavanju izločanja citokinov …

Immunoproteasome Function in Lymphocyte Activation

C Schmidt - 2019 - kops.uni-konstanz.de
The immunoproteasome constitutes a specialized form of the proteasome, a multimeric
protein complex with important functions in eukaryotic cells. Within a 20S core particle three …

[PDF][PDF] Targeting the Immunoproteasome in Health and

S Mundt - kops.uni-konstanz.de
Multiple sclerosis (MS) is a complex chronic immune-mediated disease of the central
nervous system, affecting approximately 1 in 1000 individuals in Europe and the US866 …

[PDF][PDF] Design, synthesis and biological evaluation of novel inhibitors of human and protozoan proteases

S Maiorana - 2018 - iris.unime.it
The ubiquitin-proteasome system (UPS) is the major non-lysosomal proteolytic pathway,
which plays a fundamental role in the turnover of intracellular protein of eukaryotic cells, thus …

[HTML][HTML] Crystal structures of three 4-substituted-2, 2′-bipyridines synthesized by Sonogashira and Suzuki–Miyaura cross-coupling reactions

TLT Thu, NN Bich, H Nguyen… - Acta Crystallographica …, 2017 - ncbi.nlm.nih.gov
Facile synthetic routes for three 4-substituted 2, 2′-bipyridine derivatives, 4-[2-(4-
methylphenyl) ethynyl]-2, 2′-bipyridine, C 19 H 14 N 2,(I), 4-[2-(pyridin-3-yl) ethynyl]-2, 2 …

Synthèse et propriétés d'oxindoles substitués en C-3 par une chaîne ω-aminée: application à l'inhibition du protéasome

D Sarraf - 2015 - theses.fr
Résumé Nous nous sommes intéressés au TMC-95A, un tripeptide cyclique naturel inhibant
le protéasome humain d'une façon non-covalente à des concentrations de l'ordre du …

[引用][C] NAČRTOVANJE IN SINTEZA DIPEPTIDNIH ZAVIRALCEV IMUNOPROTEASOMA DESIGN AND SYNTHESIS OF DIPEPTIDE IMUNOPROTEASOME …

K GRABRIJAN

[引用][C] Vrednotenje psoralenskih analogov kot zaviralcev imunoproteasoma:[enoviti magistrski študij farmacije]

M Marolt - 2014 - repozitorij.uni-lj.si
Največjo zahvalo bi namenila somentorici asist. dr. Martini Gobec, mag. farm. za vso pomoč
in vodenje ob izvajanju eksperimentalnega in nastajanju pisnega dela naloge ter za …