[HTML][HTML] Smart stimuli-responsive hydrogels for drug delivery in periodontitis treatment

Y Wang, J Li, M Tang, C Peng, G Wang, J Wang… - Biomedicine & …, 2023 - Elsevier
Periodontitis is a chronic inflammatory disease initiated by pathogenic biofilms and host
immunity that damages tooth-supporting tissues, including the gingiva, periodontal ligament …

[HTML][HTML] Bench-to-bedside: feasibility of nano-engineered and drug-delivery biomaterials for bone-anchored implants and periodontal applications

MF Kunrath, FA Shah, C Dahlin - Materials Today Bio, 2023 - Elsevier
Nanotechnology and drug-release biomaterials have been thoroughly explored in the last
few years aiming to develop specialized clinical treatments. However, it is rare to find …

Gingipain-Responsive Thermosensitive Hydrogel Loaded with SDF-1 Facilitates In Situ Periodontal Tissue Regeneration

S Liu, YN Wang, B Ma, J Shao, H Liu… - ACS Applied Materials & …, 2021 - ACS Publications
Existing local drug delivery systems for periodontitis suffer from poor antibacterial effect and
unsatisfied periodontal regeneration. In this study, a smart gingipain-responsive hydrogel …

[HTML][HTML] Local delivery and controlled release drugs systems: a new approach for the clinical treatment of periodontitis therapy

M Amato, S Santonocito, A Polizzi, GM Tartaglia… - Pharmaceutics, 2023 - mdpi.com
Periodontitis is an inflammatory disease of the gums characterized by the degeneration of
periodontal ligaments, the formation of periodontal pockets, and the resorption of the …

Versatile hybrid nanoplatforms for treating periodontitis with chemical/photothermal therapy and reactive oxygen species scavenging

P Wang, L Wang, Y Zhan, Y Liu, Z Chen, J Xu… - Chemical Engineering …, 2023 - Elsevier
Given the limitations of clinical curettage for periodontitis, the thorough removal of dental
plaque at deep periodontal pockets and periodontal tissue repair require improvement with …

Catechol-Modified and MnO2-Nanozyme-Reinforced Hydrogel with Improved Antioxidant and Antibacterial Capacity for Periodontitis Treatment

S Hu, L Wang, J Li, D Li, H Zeng, T Chen… - ACS Biomaterials …, 2023 - ACS Publications
Periodontitis is an inflammatory disease characterized by tooth loss and alveolar bone
resorption. Bacteria are the original cause of periodontitis, and excess reactive oxygen …

Rational designs of biomaterials for combating oral biofilm infections

Z Yin, Y Liu, A Anniwaer, Y You, J Guo… - Advanced …, 2023 - Wiley Online Library
Oral biofilms, which are also known as dental plaque, are the culprit of a wide range of oral
diseases and systemic diseases, thus contributing to serious health risks. The manner of …

Rational design of bioactive hydrogels toward periodontal delivery: from pathophysiology to therapeutic applications

Y Yin, S Yang, D Ai, H Qin, Y Sun, X Xia… - Advanced Functional …, 2023 - Wiley Online Library
Periodontitis is a biofilm‐induced, host‐mediated inflammatory disease that results in
periodontal tissue destruction. The design of functional biomaterials based on disease …

Formulation and characterization of hydroxyethyl cellulose-based gel containing metronidazole-loaded solid lipid nanoparticles for buccal mucosal drug delivery

HN Ho, HH Le, TG Le, THA Duong, VQT Ngo… - International Journal of …, 2022 - Elsevier
Local delivery of drug is a promising strategy to manage periodontitis characterized by
chronic inflammation of the soft tissue surrounding the teeth. An optimized system should …

Combining coaxial electrospinning and 3d printing: design of biodegradable bilayered membranes with dual drug delivery capability for periodontitis treatment

DM Dos Santos, SR De Annunzio… - ACS Applied Bio …, 2021 - ACS Publications
Periodontitis is a chronic inflammatory disease that can lead to significant destruction of
tooth-supporting tissues, compromising dental function and patient's health. Although the …