Contemporary epidemiology of chronic liver disease and cirrhosis

AM Moon, AG Singal, EB Tapper - Clinical Gastroenterology and …, 2020 - Elsevier
Background & Aims Accurate estimates for the contemporary burden of chronic liver disease
(CLD) are vital for setting clinical, research, and policy priorities. We aimed to review the …

Recent advances in clinical practice: epidemiology of autoimmune liver diseases

PJ Trivedi, GM Hirschfield - Gut, 2021 - gut.bmj.com
Autoimmune liver diseases are chronic inflammatory hepatobiliary disorders that when
classically defined encompass three distinctive clinical presentations; primary biliary …

Primary biliary cholangitis

A Lleo, GQ Wang, ME Gershwin, GM Hirschfield - The Lancet, 2020 - thelancet.com
Primary biliary cholangitis is an autoimmune liver disease that predominantly affects women.
It is characterised by a chronic and destructive, small bile duct, granulomatous lymphocytic …

[HTML][HTML] APASL clinical practice guidance: the diagnosis and management of patients with primary biliary cholangitis

H You, X Ma, C Efe, G Wang, SH Jeong, K Abe… - Hepatology …, 2022 - Springer
Hong You1· Xiong Ma2· Cumali Efe3· Guiqiang Wang4· Sook‑Hyang Jeong5· Kazumichi
Abe6· Weijia Duan1· Sha Chen1· Yuanyuan Kong7· Dong Zhang8· Lai Wei9· Fu‑Sheng …

[HTML][HTML] Primary biliary cholangitis: Epidemiology, prognosis, and treatment

J Trivella, BV John, C Levy - Hepatology communications, 2023 - journals.lww.com
Primary biliary cholangitis (PBC) is a chronic cholestatic autoimmune liver disease
characterized by a destructive, small duct, and lymphocytic cholangitis, and marked by the …

Goals of treatment for improved survival in primary biliary cholangitis: treatment target should be bilirubin within the normal range and normalization of alkaline …

CFM Perez, MH Harms, KD Lindor… - Official journal of the …, 2020 - journals.lww.com
METHODS: The patient cohort from the GLOBAL PBC Study Group was used, comprising of
long-term follow-up data from European and North American centers. Ursodeoxycholic acid …

The challenges of primary biliary cholangitis: What is new and what needs to be done

BT Beretta-Piccoli, G Mieli-Vergani, D Vergani… - Journal of …, 2019 - Elsevier
Abstract Primary Biliary Cholangitis (PBC) is an uncommon, chronic, cholangiopathy of
autoimmune origin and unknown etiology characterized by positive anti-mitochondrial …

[HTML][HTML] Obeticholic acid for primary biliary cholangitis

A Floreani, D Gabbia, S De Martin - Biomedicines, 2022 - mdpi.com
Primary biliary cholangitis (PBC) is a rare autoimmune cholestatic liver disease that may
progress to fibrosis and/or cirrhosis. Treatment options are currently limited. The first-line …

Cholestatic liver diseases: a primer for generalists and subspecialists

MB Hilscher, PS Kamath, JE Eaton - Mayo Clinic Proceedings, 2020 - Elsevier
Cholestasis describes impairment in bile formation or flow which can manifest clinically with
fatigue, pruritus, and jaundice. The differential diagnosis of cholestatic liver diseases is …

Contemporary epidemiology of primary biliary cholangitis

F Colapietro, A Bertazzoni, A Lleo - Clinics in Liver Disease, 2022 - liver.theclinics.com
Primary biliary cholangitis (PBC) is an immune-mediated cholestatic liver disease mainly
diagnosed in middle-aged women, with a female-to-male ratio between 4 to 5: 1 and 9 to 10 …